genetics

Your Senior Cat Can Help Discover the Genetics Behind Feline Longevity

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This is a sponsored guest post by Carolina Gonzales, R&D Coordinator at Basepaws*

Basepaws, a leading innovator in pet biotechnology, is committed to research and discovering new knowledge that will help veterinary professionals provide better care for their patients. We are developing a unique category of screening tools that combines genomic, microbiome and health history data to identify pre-clinical indicators associated with health-related outcomes.Continue Reading

Meet MezzoMixx, a Very Unusual Male Tortie

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The vast majority of tortoiseshell cats are female, because two X chromosomes are required to produce black, gold and orange coloring. Male cats only have one X and one Y chromosome, so technically it’s genetically almost impossible for a male to inherit the tortoiseshell coloring. A male tortoiseshell has an extra X chromosome, making it an XXY. According to a study by the College of Veterinary Medicine at the University of Missouri, only 1 in 3,000 tortoiseshell cats is male. Due to the chromosome imbalance, male tortoiseshell cats are (usually) sterile.Continue Reading

99 Lives Whole Cat Genome Sequencing Initiative Could Bring Advances to Feline Health

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A team at the University of Missouri, led by renowned feline researcher and associate professor Leslie Lyons, will map the genes of 99 cats. The project will map 20,000 genes to develop a complete portrait of feline genetic make up.

The 99 Lives Whole Cat Genome Sequencing Initiative could help identify the cause of cats’ fur and eye color, and, more importantly, the source of feline health problems. It could even support research on diseases that affect both cats and humans. “When a sick cat comes along, you could genetically sequence it and say, ‘Hey, look, this has a variation we’ve never seen before,’ ” Lyons told the San Francisco Chronicle. “It might give us clues very quickly as to what genes to focus on for this cat’s health care.”Continue Reading

Tortoiseshell cats show limits of cloning

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Cloning pets is a relatively new, and very expensive, procedure. It not only raises ethical questions about whether pets should be cloned when there are thousands of adoptable pets in shelters and at risk of being killed, but the few pet owners who have had their pets cloned have come to realize that while the cloned pet may look like their favorite departed pet, his or her personality may be completely different from the original.

While I won’t even try to understand the science and mechanics involved with cloning, I do have a basic understanding of genetics, and I really know tortoiseshell cats. Those of us who love cats with this distinctive coloring also know that they are very unique when it comes to their personalities, often known as “tortitude.” And now scientists are finding that tortoiseshell cats also show the limits of cloning.Continue Reading

Meet Doodlebug, a rare male tortie

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It’s no secret that I love torties. From my first office cat Virginia, to Amber, Buckley, Allegra and Ruby, there’s just something about these cats’  particular coloring, and their unique personalities, that has always appealed to me.

Tortoiseshell cats are named for their coat color, which is a mottled or brindled combination of brown, black, tan, gold, orange, and sometimes cream and blue. Those of us who fancy torties know that they have unique personalities, often referred to as “tortitude.”

They also have unique genetics. The vast majority of tortoiseshell cats are female, because two X chromosomes are required to produce black, gold and orange coloring. Male cats only have one X and one Y chromosome, so technically it’s genetically almost impossible for a male to inherit the tortoiseshell coloring. A male tortoiseshell has an extra X chromosome, making it an XXY. According to a study by the College of Veterinary Medicine at the University of Missouri, only 1 in 3000 tortoiseshell cats is male.

Given all that, it’s no wonder that I was excited when I came across one of these rare male torties.

Doodlebug belongs to Sharon, one of our readers. He is 16 months old and is the son of Sharon’s other tortie, Callie. The fact that he was a he came as quite a surprise to Sharon. She actually called him Chloe for the first couple of months of his life, and she was caught rather off guard when she took him for his first vet visit. I asked what the vet’s reaction was when he realized that he had one of these rare male torties as a patient. “He was actually pretty matter of fact,” reports Sharon. “He told me that he would change the gender notation in the record, and that I might want to find another name.”

Male torties are believed to be sterile. Doodlebug is currently unneutered, but, says Sharon, “that will change the first time he sprays something.” He’s an indoor cat with limited access to an enclosed yard, and her other three cats are spayed. Doodlebug has shown no interest in roaming, spraying, or mounting the other cats. The vet has given him a clean bill of health.

As for tortitude, Doodlebug appears to be more laid back than the average tortie. He is very mellow, and likes to spend hours drowsing next to Sharon while she is on the computer or watching tv. He can be a bit possessive when one of the other cats takes over “his” side of the chair, but he’s very gentle about nudging them out of his territory. Eating is another favorite past time. In addition to his regular diet of dry cat food, he enjoys sampling the regional cuisine, including fried catfish and crawfish. He also loves chicken and sausage gumbo and will happily eat even the okra in it.

Because of their genetic rarity, some people mistakenly believe that male tortoiseshell cats are worth a lot of money. In reality, they’re only worth as much as any other cat who is loved and valued by their owners, and as we all know, there is no price tag on love.

Doodlebug is unaware of his newfound fame and remains unavailable for comment.

Photo of Doodlebug used with Sharon’s permission

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Tortitude: the unique personality of tortoiseshell cats