When Cats Refuse to Take Pills

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When it comes to giving pills to pets, dog parents tend to have it easier. Put the pill in a little bit of peanut butter or cheese, and most dogs will think they’re getting a treat and wont’ even notice the pill. When it comes to cats, it’s usually not quite that simple. Rumor has it there are some cats who will allow their owners to pill them easily, but if my personal experience and that with veterinary clients is any indication, they’re few and far between.

Options for pilling cats

There are several options for pilling a cat, from quickly shoving the pill deep into the cat’s mouth to using a pill gun to pill pockets to Pill Masker to crushing up the pill and mixing it with a small amount of food (caution: the latter may not be appropriate for all types of medication, check with your veterinarian to be sure.)

Many medications are also available in liquid form, which may make dosing easier for some cat owners. Some can even be compounded into tuna or chicken flavored liquids. Another option may be transdermal delivery: the medication is compounded into a cream that is rubbed on the inside of the cat’s ear.

And of course, there’s always the ever popular kitty burrito method (although I’m sure cats would disagree with its popularity).

In theory, all of these sound great. But there are some cats who simply won’t cooperate. And unless you’ve had one of these cats, you may not understand the emotional toll this can take on the owner.

There are some cats who simply won’t cooperate. And unless you’ve had one of these cats, you may not understand the emotional toll this can take on the owner.

Cats who refuse to take pills, and the humans who love them

I recently talked to a friend whose 16-year-old cat was diagnosed with hyperthyroidism, and needs to take medication twice a day to regulate thyroid function. She can’t pill the cat, he won’t take pill pockets, and he refuses to take the liquid form of the medication in his food. She tried the transdermal version, to no avail. She kept trying, for several weeks. At this point, the cat runs from her whenever he sees her coming. He no longer sleeps on the bed with her, or sits next to her when she reads or watches TV. The bond between the two of them is completely broken. My friend is stressed and upset, and so is her cat.

The bond between cat and human is completely broken.

The cat is not a candidate for radioactive iodine treatment, nor is he a good candidate for surgery. The medication is the only viable option to control his disease. My friend is at the end of her rope: she feels like she’s killing her cat because she can’t medicate him, and most of the time she feels like she doesn’t even have a cat anymore since he wants nothing to do with her.

Sometimes, deciding not to medicate is the right answer

I told my friend that she has another choice. Making a treatment decision can also mean choosing not to treat. She can choose to stop giving her cat the medication, and restore the relationship with her cat. She will need to understand what will happen physiologically to a hyperthyroid cat with no treatment. She will need to accept that this will most likely shorten her cat’s life. She will need to monitor her cat closely for even subtle changes, and she will probably eventually need to be ready to make the euthanasia decision.

She’s afraid to tell her vet that she wants to stop treatment. Understandably, this may not be a popular decision with some vets. Vets are trained to heal and cure. But most vets also understand that they’re not just treating their patient, they’re treating the bond between patient and human. And when treatment interferes with the bond to the extent it did for my friend, shouldn’t they discuss this alternative with their clients?

Most vets understand that they’re not just treating their patient, they’re treating the bond between patient and human.

Deciding to stop treatment: my personal experience

I had to make this choice with Buckley. I was fortunate that I had my vet’s complete support when I decided to stop treating her restrictive cardiomyopathy. She was on multiple cardiac medications, and for several months, she happily took them with pill pockets. Once she started to refuse the pill pockets, the only way I could have gotten the meds into her was through force. Buckley was the kind of cat who, at a mere seven pounds, needed multiple veterinary assistants to restrain her to get anything done. I don’t think she ever had an exam that didn’t require at least mild sedation. There was no way I could have pilled her, nor would I have wanted to put a cat with heart disease through the twice daily stress of it. I also knew that she would come to dread contact with me, and I knew I couldn’t have handled that.

I made the choice to stop her heart medications, knowing full well that it would shorten her already much too short life even further. But I also knew it was the right decision for her, and for me. She lived for another month after I stopped her meds, and except for the last few days of her life, her quality of life was good.  If anything, our bond became deeper, knowing that our time together was limited.

If my friend chooses to stop treatment for her cat, she will most likely shorten her cat’s life, too. But what she will gain, in my opinion, far outweighs what she will loose. She will get the loving relationship with her cat back.

This post was first published in April 2011, and has been updated.

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122 Comments on When Cats Refuse to Take Pills

  1. vickie
    June 21, 2020 at 6:11 pm (2 months ago)

    I have 13 year old female orange tabby. She’s feisty through and through, but loves her momma dearly. She was diagnosed with IBD a year ago, and up until a month ago, would for the most part, take her medicine crushed into various types of soft food. That medicine no longer was working for her symptoms, and it is believed that her IBD has turned into lymphoma which is quite common considering the amount of imflammation in the bowels. She was prescribed a permanent dosage of prednisone, cerenia for nausea and metronidazole. She took the meds the first couple of days and now hasn’t touched it in five. This is our last option for her to extend her life and lessen the flare ups and side effects that come with it. Making that decision to no longer give medication creates a ticking time bomb. As soon as those meds exit her system, her symptoms will be severe. She is bony, and has lost an incredible amount of weight. Unless she miracuroulsy decides to take her medicine, I will have to make a difficult decision in the coming days. I don’t want her to suffer more than she will have to. I wish we were able to communicate with our fur babies about their medicine and why they need it!

    • Nancy
      July 13, 2020 at 1:39 am (4 weeks ago)

      I have 2 cats I’m pilling – twice a day for one and once a day for the other. The only way I can give a pill is with a pillar. I know it depends on the cat but in both cases, I’m able to do it but I have to do it fast and kind of sneak up on them. I’m sorry I’m just seeing this now as I’m behind with my emails. I hope she is doing ok and I know what a hard time this is for you. I’m so sorry.

  2. Shannon
    June 12, 2020 at 8:14 pm (2 months ago)

    I also have a cat who’s been recently diagnosed with restrictive cardiomyopathy. He’s always been an anxious cat, but we have an incredible bond. He’s been taking his meds in food for 2 months, but the other day started refusing everything I offer him.
    I am a cat lady who’s been in the veterinary field for 15 years, I know all of the tricks, and lately I am so frustrated, tired, and emotionally drained.
    I have been torn whether I should stop treatment or continue trying – which has resulted in him running away in fear every time I go near him lately.
    Thank you for this article. It’s comforting to know that you are happy with your decision to have stopped treatment and enjoyed the time you had left with your feline friend.

  3. Nancy Cowan
    August 3, 2019 at 10:04 pm (1 year ago)

    My cat Maggie, who is turning 16 this month, is hyperthyroid. I was feeding her Y/D for a few years and it worked well but was difficult as I have other cats. She is now getting Felimazole, a little pink pill, twice a day with a piller. Fortunately she is easy to pill and I know this isn’t always the case. If a piller doesn’t work, try Y/D. I bought that from my vet and it’s made by Science Diet.

  4. Betty
    August 2, 2019 at 9:34 am (1 year ago)

    I am currently dealing with this problem with my senior gal and hyperthyroidism – 2 pills a day . Pill pockets worked for awhile then pill paste, there is no way I can give her a pill. She won’t eat anything because I’ve been hiding the pill in it. Some days there will be 3-4 cans of food open until she decides to eat something. I’m at the point of if she eats it great, if she won’t she won’t. The stress to her and me doesn’t make it worth it for this 14 yr old kitty. I certainly understand your option to not medicate, I’ve been thinking this way for a while.

    • Nancy Cowan
      August 3, 2019 at 10:28 pm (1 year ago)

      Betty – I just want to add to my comment about feeding Y/D. First of all it is made by Hill’s. And also, if you decide you are interested in trying this, of course talk to your vet. I know it works in a different way then Felimazole but I can’t remember the details without researching it again so you may want to do that first. It is just another option if you can’t pill and it definitely worked for Maggie for at least 3 years until I found out about Felimazole.

  5. Caz
    June 28, 2019 at 7:15 pm (1 year ago)

    When my cat was Ill. And he didn’t want tabs. I put the pill in a sticky. The long cat sticks they pliable you can hide the pill and hold it so it is completely covered worked brilliantly for my cat. Who was v clued up.

  6. Nat
    June 28, 2019 at 4:08 am (1 year ago)

    I’ve been struggling with my cat to give her medication 3x daily. I am so stressed out and so is my cat. She’s hiding from me and when I do ‘catch’ her she bites and scratches me. The vet says she needs the meds to fight a bacterial infection. I do believe her but I cannot do it like this for a month. I’ve decided to offer it to her with her food. If she eats it, great. If not… I need to let it go.

    So far she might have ingested her meds, or not, but she’s already happier…. going outside, enjoying the sunshine, hunting for mice. I don’t know how much longer she’ll have but it’s no longer up to me. I’ve done my best and I will take her to the vet if she’s running a fever again or becomes lethargic but I’m not going to fight with her and shove a pill down her throat which she will puke out half an hour later.

    Thank you for this article. I needed this.

    • Ann Heatherton
      July 31, 2019 at 10:41 pm (1 year ago)

      Your vet could have given your cat a convenia injection which is a slow-release long-lasting antibiotic to fight infections. Then you would not have to go through this house’ll. Please ask for one of those next time.


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