RenAvast: A Solution for Chronic Renal Failure in Cats?

RenAvast_kidney_function

During a recent visit to my vet’s home to do a Reiki session for 17-year-old Fifi, who is in renal failure, my vet mentioned that she is giving Fifi a new supplement called RenAvast™, and that she was really pleased with the results. I wanted to find out more about this supplement. What I learned impressed me enough to introduce you to it.

Physiology of Chronic Renal Failure

Chronic renal failure in cats is a physiological condition in which the kidneys have lost some degree of functional capacity. The kidneys’ ability to filter and remove waste products from the blood, and to regulate electrolytes is compromised. By the time symptoms appear (such as weight loss, vomiting, diarrhea, increased thirst and urination, dry haircoat), two-thirds to three-quarters of the total functioning kidney tissue may already be lost.

Management of Chronic Renal Failure

Management of chronic renal failure involves managing symptoms by increasing hydration, decreasing the buildup of toxins in the blood, treating any possible underlying reversible disease (infection, hyperthyroidism), maintaining good blood flow to the kidneys, and minimizing any further damage. These therapies are designed to slow down the disease and maintain good quality of life, but there is no cure for renal failure.

Research Supporting RenAvast™

RenAvast may be a game changer. A 2-year study with 19 cats showed dramatic results:

  • 89.5% of the cats had creatinine values that improved or did not deteriorate
  • 84.2% of the cats in the study had BUN (blood urea nitrogen) values that improved or did not deteriorate
  • 94.4% of the cats in the study had phosphorus values that improved or did not deteriorate
  • 100% of the cats in the study had urine specific gravity values that improved or did not deteriorate
  • 94.7% of the cats in the study had hematocrit values that improved or did not deteriorate

Elevated creatinine, BUN and phosphorus levels are an indicators of renal disease. Low urine specific gravity and hematocrit values (a measure of the concentration of red blood cells) are also indicators of renal disease.

How does RenAvast™ work?

RenAvast is a combination of amino acids and peptides. According to BioHealth Solutions, the company that makes RenAvast, cats have seen improvement in their kidney function within weeks of starting the supplement. It is said to be 100% safe with no side effects, and can be used with other drugs and supplements. RenAvast can be mixed with a small amount of food to ensure that the cat eats the entire amount, or it can be mixed in a syringe with water and given directly by mouth.

RenAvast™ Testimonials

“I started 3 different cats (with different levels of kidney dysfunction) on RenAvast™ at the same  time. In about 3 weeks (and within days of each other), each owner called me back and told me  how great their cats were doing. That they were eating better and seemed happier and had more  energy. We repeated bloodwork on each of the cats. One had a decrease in kidney blood values  and the other 2 were holding steady. Needless to say, the owners and I are all thrilled with your  product. Thanks.” – J. Levitsky, DVM

“RenAvast™ has been very useful in stabilizing my feline patients with renal disease. I have been recommending RenAvast™ for about 8 months now and 98% of my feline patients respond with increased appetite, increased weight gain, an improvement in the BUN and creatinine levels, and increased energy. It is the most helpful supplement I have found yet for feline kidney disease.” – A. Sagrera DVM, CVH

“If you area at a loss for what to give your cat, give RenAvast™ a try. I was told I would need to put my 13-year-old cat down in December. This is after giving her 100 cc’s of subcutaneous fluids daily, along with Epakitin and Azodyl. I ordered the RenAvast™ as a last resort. Within a few days of taking it, her appetite increased, and she didn’t seem so lethargic. I took her for bloodwork, and her creatinine went from 9.4 to 6.3. It has now been almost three months, and she is doing well.” – Rebecca Brown

For more information about RenAvast, please visit http://www.renavast.com/. RenAvast can also be used for dogs.

Editor’s note: I am not affiliated with RenAvast or BioHealth Solutions. I shared information about this product because my own vet was pleased with the results she saw in her own cat, and in her clients’ cats, and because I thought it might benefit my readers.

This post has been closed for comments.

128 Comments on RenAvast: A Solution for Chronic Renal Failure in Cats?

  1. Gabrielle
    August 11, 2015 at 11:27 am (4 years ago)

    I used to get RenAvast for my cat but the last time when my husband picked it up at our vet he was handed AminAvast instead. When I noticed and did some research I came across this website and the very interesting comments! Thanks so much to all of you for the info; I wrote my (holistic) vet and am waiting what she says. Does anybody else know if AminAvast is RenAvast just repackaged? Unfortunately I threw out the old bottle and can’t check the ingredients…

    • Elizabeth
      August 11, 2015 at 4:08 pm (4 years ago)

      Gabrielle, I just re-ordered Renavast for my cat. It is now called AminAvast. It is the same product, new name. My cat has been on this supplement for many months now, is doing fine. She is 15. I supplement it with SubQ fluids, potassium supplement, and quality (as natural as possible, and lower sodium) wet food, per my holistic vet’s suggestions and prescription. My vet is treating 4 of her own cats (she has several) who are CRF and gives them the Renavast/AminAvast. My vet is the one who introduced me to Renavast I think it was over a year ago.

    • Lisa
      August 23, 2015 at 1:36 am (4 years ago)

      Aminavast is Renavast. For some reason the company was required to relabel this product. I use it at the recommendation of my holistic vet.

  2. Elizabeth
    July 25, 2015 at 2:25 pm (4 years ago)

    Response to Anjali, and a general comment re: Renavast:

    I did check with my vet who is both allopathic and holistic. She researches supplements carefully, as she also has CRF cats, as I do. She has been giving her cats Renavast for some time, as I have been doing for mine. She said they are all doing fine, as are mine, that as a supplement, it can’t hurt.

    She said Renavast is a relatively new natural supplement, and not as many studies on it.

    I hope that more companies will produce some naturalistic/holistic supplements for cats, as there is a real need for this. Especially for the CRF and the high thyroid issues that seem to be so common. It would be good if all of us cat owners would consider how to feed them a healthy cat diet to prevent the onset of these things. Just like people need to eat healthier, live healthier, to prevent the type II diabetes, and cancer that are the feline CRF, high thyroid counterparts to these older cat diseases.

    • Anjali
      July 25, 2015 at 2:57 pm (4 years ago)

      Interesting to read all the other regimens for CRF. It’s certainly an individual decision for each of us. Wishing the best for all the kitties.

    • Ingrid
      July 25, 2015 at 3:12 pm (4 years ago)

      That’s how I first heard about Renvast, Elizabeth: my own vet was giving it to her cat. That’s when I decided I wanted to write about it so more people would be aware that this is out there (or was, as the case may be.) And I agree with Anjali, it’s always an individual decision, whether it’s about a supplement, a conventional drug, or anything else when it comes to our cats’ health.

      And I also agree with you, Elizabeth: a species-appropriate diet can prevent many of the degenerative diseases we’re seeing in cats. Nutrition isn’t the only thing that contributes to these diseases; there are, of course, other factors. However, I’ve always felt that while We can’t control our cats’ genes, and we can only control their environment up to a point, we CAN control what we feed them.

  3. Caroline
    July 24, 2015 at 1:50 pm (4 years ago)

    I see that Jane Garrison, the admin for the Feline/Canine Chronic Renal Failure Facebook Group page, is married to the owner of the company that makes RenAvast. I always wondered if she was a paid spokesperson, as she was adamant about starting kitties on it right away. I never saw any disclosure.

    • Caroline
      July 25, 2015 at 6:58 pm (4 years ago)

      I guess no one cares that the owner of RenAvast started a FB Group about renal disease, recommending her product, and I never saw a disclosure.

      • Rose
        July 25, 2015 at 10:48 pm (4 years ago)

        Caroline, I do care, and so should everyone else as it shows the dishonesty of the owners of the company. They also have gone around to message groups posting as if they are customers and giving themselves outstanding product reviews. This is downright fraudulent.

      • Ingrid
        July 26, 2015 at 6:38 am (4 years ago)

        I’m sad to hear that the company appears to be using these types of marketing tactics. I would like to be very clear that I am not affiliated with RenAvast or BioHealth Solutions. I shared information about this product because my own vet was pleased with the results she saw in her own cat, and in her clients’ cats, and because I thought learning about it might benefit my readers.

        • Rose
          July 26, 2015 at 9:51 am (4 years ago)

          Here is an example (Amazon pulled all of the reviews, and many of the early ones were done by the Garrisons and their employees)

          This post is by Jane Garrison, wife of owner Mark Garrison, and she mentions her cat Tuffy.
          View previous comments

          Jane Garrison Oh yes….stress, fish and dry food are the three triggers for my cat Tuffy.
          December 20, 2011 at 9:21am · Like · 1

          This “testimonial” is on Eco Pets Italia:
          http://www.ecopetsint.com/testimonials-23.html
          Jane G. of Redondo Beach, CA
          “When our 14 year old cat Tuffy was diagnosed with the beginning of Chronic Renal Failure (CRF) I was very upset. I knew that CRF only gets worse as cats get older and I hated the thought of losing him to this disease. A friend told me about a clinical study that was taking place for RenAvast and I immediately enrolled him. At the time Tuffy was enrolled, his creatinine level was 2.5 which is outside the normal range. I was very diligent about giving him the RenAvast twice a day in his food which he ate with no problem or side effects. I recently had his kidney values checked and his creatinine level is now at 2.1 which is normal! Thank you RenAvast for extending Tuffy’s life!!! I now have all my cats on it to prevent kidney disease.”

          So, now we have confirmation that at least one of the 9 “enrolled” cats in the “study group” belonged to the owners!!

          • Rose
            July 26, 2015 at 9:54 am (4 years ago)

            and further down the page is a review by “Dr Garrison”:
            Dr. Garrison, Los Angeles, CA
            “My wife is typically the one who handles the health care of our cats. However, when she told me that she wanted to put our cat on a new product I was very skeptical. Being a doctor myself, I have seen products come and go with false expectations. I have seen products make outrageous claims that are not backed up by science and research. However, after reading the research about RenAvast and seeing the results our cat Little has had…I am sold. Finally a product that is actually backed with true science. Our cat Little now has normal kidney values and I am confident that he will live a long life with healthy kidneys.”

        • Caroline
          July 26, 2015 at 3:56 pm (4 years ago)

          Oh course, Ingrid. We know that, and very much appreciate all of the helpful information we get from you.

        • sandra
          November 26, 2015 at 7:13 pm (4 years ago)

          Ingrid: I’m sorry to hear that you took these comments at face value. Did you verify these comments? The FB Group for the renal pets was started by Rob Girolo, not renavast as was stated. Also, all online pharmacies require that the comments be verified by either a FB account, Amazon account or an email account. You can’t just post comments without being vetted.

  4. Rose
    July 24, 2015 at 10:10 am (4 years ago)

    Your arguments about supplements are valid, however, the behavior of this particular company is very shady, which is outlined in the legal complaint. Their “scientific” study had no controls and was laughable. The company also took steps to deliberately evade the law. This company reminds me of a typical propagandist, they even have gone so far as to post fake reviews of their products. I traced some of their Amazon reviews and message board comments praising the product back to Mark Garrison and his wife. What legit company would need to do this?
    Fluids are the most helpful thing for a CRF cat and are a proven therapy. Don’t waste your money on something like this .. people think it is helping because they want it to help. I would have done anything or spent anything to help my pets, and that is exactly the emotions that this company is preying upon. Their shady, unethical business practices should be a big red flag as to what they are about.

    • Anjali
      July 24, 2015 at 9:50 pm (4 years ago)

      Thanks for this. As I mentioned in my comments below, I’m skeptical as well. I passed along the info and links to my vet, and he did some research. He concluded that we should *not* give RenaVast to my Luna. To paraphrase his long and thoughtful response to me, my vet essentially said that he’s concerned about the ingredients, including Avastamine, which is not an amino acid. He believes the studies cited are highly suspect, that there is no time frame, no controls, no blinding, a small sample, and a host of other problems with the data. He believes there are lots of reasons to question RenAvast, including proprietary ingredients, sketchy studies, no independent manufacturing or quality control oversight. He can’t conclude that it would do no harm. He is open to using a variety of other supplements and medications that have more robust studies and data to support their use. So in addition to the fluids, which we will continue to give Luna every two or three days, we will be considering other options when he rechecks her next week. Thanks so much.

      • Elizabeth
        July 24, 2015 at 11:34 pm (4 years ago)

        Anjali, Is your vet holistic or allopathic? Often the allopathic vets are skeptical of natural supplements/treatments as are allopathic drs. for humans. For natural supplements for my cat, I always consult with my vet who is holistic in her approach. Although she does use modern medical drugs/treatments alongside natural ones. Of course, Renavast may not be for every cat either.

        Tests and studies on natural supplements are often non-existent, as I said in my earlier comment. True also of natural supplements for humans. Means public and mainstream drs. are often skeptical of natural treatments, as the big drug co.’s have a much easier time swaying public opinion against natural supplements/treatments due to their huge funding resources for promoting their drugs and for funding their own drug studies.

        • Anjali
          July 25, 2015 at 8:32 am (4 years ago)

          My vet is traditionally trained and is also a member of IVAS (International Veterinary Acupuncture Society). He has been practicing for around 25 years in various capacities and is regularly undergoing ongoing education. He and I are open to treatments, natural or otherwise, that could improvs Luna’s quality of life and *do no harm.* However, if a product is not properly tested with the scientific method and there is no independent regulation and oversight, I could be feeding her a pill made of grass, celery powder, filler or something potentially toxic and I wouldn’t know it. My job is to protect her and I’m not willing to turn her into a test subject for potentially harmful substances.

          • Anjali
            July 25, 2015 at 8:36 am (4 years ago)

            I meant “improve,” not “improvs.”

      • angela
        September 3, 2015 at 12:21 pm (4 years ago)

        My cat was just diagnosed with chronic kidney failure last week, but doesn’t mention this fluid treatment at home or anything but low protein cat food. He doesn’t seemed to be concerned or care. I would like to know what medications would help.

  5. Elizabeth
    July 23, 2015 at 7:02 pm (4 years ago)

    In response to many of the more recent comments: Renavast is a natural supplement. As Ingrid said, there are few funded studies on natural supplements, true whether for humans or pets.

    Most commentors here probably know that the reason for this is that, for humans, and likely for pets too, Big Pharma (all the big drug co.’s) cannot patent and make money off of the food or vitamin supplement products, so, they are relatively, no greatly, underfunded, or non-existent. Therefore, these supplements, for humans and pets alike, are quite susceptible to attacks from “skeptics” and “quack hunters” since the natural supplements aren’t considered “mainstream.” Regardless, it’s always a good idea to investigate natural supplements just like with mainstream medical drugs.

    If the Renavast were really that “suspicious” or “bad” or whatever, my cat, who already has delicate health, would not be doing so great right now.

    In many cases, whether for humans or for pets, often times the natural supplementation, treatments, and holistic diets are a life-saver, or greatly life-enhancing where the modern medical treatments and drugs have failed, which is all too often.

    Cats, like people, are each unique. They each need unique combinations of supplementation and/or medications. In my case, my 15-year-old female cat has been on Renavast for about a year and a half now, at the suggestion of the holistic vet we go to, based upon the blood and urine tests that we obtain for our cat. We had to switch her off of dried pellet food, which I regret to say, I wish I had realized much earlier on in her life, that the dried pellets maybe are not so great for cats. I wish I had considered way earlier on how to prevent CRF in the first place.

    My cat is doing very well, although the CRF is progressing; little anyone can do about that using natural supplements or not, unless you are able to catch it at a really early stage, possibly. Her regimen, unique to her, includes: Renavast, Methimazole (for high thyroid condition), Renal K, Proviable, B12 injections every couple weeks, subcutaneous fluids every 3 days, Zeniquin for UTI’s, high quality cat food that is not low protein, KD cat food, and other types of high quality cat food, plenty of FRESH R/O FILTERED water, antibiotics when needed, and lotsa TLC. BTW, she is indeed indoor only.

    My vet investigated D-mannose (not the usual cranberry extract, a no-no for CRF cats) as a possibility to give to her to prevent future UTI’s to which CRF cats are susceptible and felt this would be fine to give to her.

    Point is, likely in the case of most CRF cats, Renavast, if administered, may need to be done so in conjunction with other supplementation and meds, and through consultation with a holistic vet.

    • Anjali
      July 23, 2015 at 8:02 pm (4 years ago)

      I’m glad your cat is doing well, and thanks for all the great info. Thanks for your reply to my second comment as well, Ingrid. I’m passing along the comments to my vet and we’ll talk about the options. I’m also weighing Luna’s quality of life against her stress level in terms of administering interventions and what she will tolerate reasonably well. We had her on a Calcitriol supplement and recently an injectable antibiotic for tooth and gum issues, and now she’s on Cerenia for a few days to try to calm her GI upset. We also give her subcutaneous fluids every two or three days as well as probiotics. I’m well aware that natural remedies can’t be patented and so don’t receive the research funding and attention that Big Pharma gives to drugs. I’m in favor of natural care, and I’m also aware that if a supplement is not monitored or regulated, problems can occur. Take the case of the recent testing of supplements for humans and the discovery that many contained fillers – carrot and celery powder, for example – instead of what was on the label. So I’m trying to be careful to do my research and I think a healthy dose of skepticism is not a bad thing along the way.

    • Ingrid
      July 24, 2015 at 6:23 am (4 years ago)

      I’m glad to hear your cat is doing so well, Elizabeth, and thank you for sharing your perspective.

    • angela
      September 3, 2015 at 12:36 pm (4 years ago)

      My cat is 15 yrs old and had been diagnosed with chronic kidney failure just last week, but the vet didn’t seem to really care and only suggested the KD cat food which for my cat, he will only eat the dried cat food, will not eat any canned cat food. He didn’t mention any type of fluids to do at home or any medications at all. He also was diagnosed in June with a spinal cord tumor that is cancer and maybe he thinks there is no use to worry about the kidney failure, but I would like to try and help it from getting any worse, especially with all he has going on.

      • Ingrid
        September 3, 2015 at 1:13 pm (4 years ago)

        It sounds to me like you need to find a new vet, Angela. Given that your cat has multiple issues, you may want to consider seeing a vet who specializes in internal medicine. At the very least, I would work with a vet who offers more help than just suggesting dry k/d. Protein restriction is not indicated until the final stages of renal failure, because it causes muscle wasting, which is associated with decreased longevity and quality of life. We know now the cats will use amino acids in their own muscle if inadequate protein is fed. Keep trying to encourage your cat to eat wet food. Here are some tips on how to transition cats from dry to canned food: http://consciouscat.net/2011/07/25/how-to-your-cat-off-dry-food/

        • angela
          September 3, 2015 at 2:11 pm (4 years ago)

          His creatineane level was at 2. 5 and sorry for the misspelling. I have had him to two vets, we don’t have any internal med vets close where I live, and both vets said he needs to be on the low protein food. I have tried and tried, but he will not eat wet cat food, only the dry. I don’t know what to do now. Sounds like he doesn’t need to be on that food, so very upset.

          • angela
            September 3, 2015 at 3:24 pm (4 years ago)

            I think his bun was a little high, but he just won’t eat wet food. The only wet thing he will eat is tuna fish out of a can, he loves that, but has protein. Do you think the science hills KD formula cat food for renal failure is ok, or would he need more protein and if yes, what kind of cat food would have a good protein? I also read about a product called azodyl, are you familiar with that?

          • Ingrid
            September 3, 2015 at 3:33 pm (4 years ago)

            Keep trying on the wet food, Angela. Have you tried all the tips provided in the two articles? I have yet to see a cat who can’t be transitioned. Azodyl helps support renal health. However, since you’re also dealing with a cat with cancer, I don’t know whether Azodyl is okay to give. You really need to find a vet to work with who can treat both conditions and who you can trust. You may need to travel a bit further, but it may be worth it both for your cat’s health and your peace of mind.

          • angela
            September 3, 2015 at 4:12 pm (4 years ago)

            I have already spent over 5,000.00 on his bills, and I am out of a job atm. I really don’t have anymore to spend. I hate this.

  6. Caroline
    July 22, 2015 at 11:59 pm (4 years ago)

    I commented earlier that my kitty was not maintaining on RenAvast. I do not want to discourage anyone from using. I started giving my kitty fluids every 3rd day, along with giving RenAvast and Azodyl and she is doing very well. 2 years in. 16 yrs and happy today.

    • Ingrid
      July 23, 2015 at 6:06 am (4 years ago)

      Thank you for the update, Caroline. I’m so glad your kitty is doing well.

      • Anjali
        July 23, 2015 at 9:39 am (4 years ago)

        Ingrid, I just did a little online research on Renavast as Luna has renal disease. It appears the FDA has just banned Renavast. Any comments on this?

        • Ingrid
          July 23, 2015 at 9:50 am (4 years ago)

          It is true that the FDA filed an injunction against Bio Health Solutions, the makers of Renvast. I want to be clear that the injunction addresses how the product was marketed, not the product itself. Unfortunately, this will mean that the product will not be available in the US until it is relabeled. When I asked BHS about it, they responded immediately with the following statement:

          “Bio Health Solutions denies the allegations within the complaint that it sold an adulterated and unsafe animal supplement. While Bio Health Solutions did create a password protected part of its website after receiving a warning letter in 2012, it did so on the advice of a prominent boutique food and drug law firm that assured BHS and Mr. Garrison that it was permissible to do so as long as the site was only accessible to veterinarians. Indeed, FDA is fully aware that this practice is common place in the animal supplement veterinarian business and has not generally objected to it until it sought a consent judgment with BHS. BHS denies that it ever purposely attempted to evade FDA’s rules regarding marketing claims and was simply following the advice of counsel or conceal its business practices. BHS looks forward to working with FDA on issues related to the use of appropriate marketing claims for animal supplements sold in the veterinarian channel in the United States. BHS is also committed to working with FDA to take RenAvast through the animal drug approval process as it has done internationally. To date, RenAvast is cleared for marketing in 6 different countries. BHS looks forward to being able to reintroduce RenAvast in the United States after it receives approval. In the meantime, it will work with FDA to assure that international products are not diverted into the stream of commerce in the United States.”

          On an unrelated note, Bio Health Solutions announced the launch of a new supplement to support healthy kidney function in cats and dogs. AminAvast will be made available though veterinarians and online retailers beginning this week. You can find more information at http://www.aminavast.com. For all of you who are using Renavast with good success, you may want to contact your veterinarian for advice on whether your cat can take Aminavast until Renavast is available again in the US.

          • Anjali
            July 23, 2015 at 10:11 am (4 years ago)

            Thanks for this, Ingrid. A few things concern me. One is that when I do a Google search for Renavast, all the company information comes up first, and next, all the sites that sell Renavast. I’m looking for some hard science and stats on the drug. Most of the info or PR comes from the company. Why would the company not have known to take the appropriate steps to market the drug in the U.S.? I’m not saying it doesn’t work. But without any regulation or monitoring, how do I know Renavast contains what the company says it contains? Or that the ingredients work the way the company says they work? The FDA announcement notes that a warning letter was sent to the company in 2012. Did the company then take steps to correct the situation? It’s now 2015. I found this one SkeptVet.
            http://skeptvet.com/Blog/2014/03/renavast-for-kidney-disease-sloppy-science-and-snake-oil-marketing/
            I’ll discuss all this with my vet, as I would love to do everything I can to help my Luna, who is 16 and has renal disease. I am cautious, however.

          • Ingrid
            July 23, 2015 at 4:21 pm (4 years ago)

            Renavast is not a drug, it’s a supplement. My understanding is that the FDA got involved because they claim BHS marketed it as a drug. You’ll have to decide for yourself whether you’re comfortable with it, Anjali, and of course, discuss it with your vet. As for Skeptivet, he/she trashes holistic modalities in general, not just this particular supplement. I’m not going to comment on whether his/her views are right or wrong, but the sad reality is that there is very little funding for studies about alternative modalities and supplements, so studies may be few and far between, and are often funded by the makers of a product. FWIW, I would use Renavast for my cats without hesitation.

          • Anjali
            July 23, 2015 at 8:10 pm (4 years ago)

            Thanks for the second reply, Ingrid. I’m very much aware that holistic remedies can be very helpful and don’t get the same research funding as Big Pharma, but I also believe my caution and skepticism as I do the research is quite healthy, considering, for example, the recent study by a consumer research organization showing that many supplements for humans contained fillers instead of what was on the label. I’m protective of my animals for all the right reasons. Luna is on Cerenia at the moment for a GI upset. She was on an injectable antibiotic for tooth and gum problems, and Calcitriol for the kidney disease. We’re giving her fluids every two or three days. We’re trying to balance lots of issues with her, and of course I want the best for her. I’m passing along all the comments to my vet and he’s going to look into it and get back to me. Our position is at this point, if it can’t *hurt* her, it’s worth a try. Of course at the moment it seems we can’t get the RenaVast anyway…

          • Ingrid
            July 24, 2015 at 6:19 am (4 years ago)

            It is true that there is not much regulation when it comes to supplements, and it is up to the consumer to do their own research, Anjali. Please post your vet’s comments so others can benefit as well.

            Kidney disease can be challenging to manage, especially when you’re balancing multiple issues. All my best to Luna!

  7. Beth
    July 18, 2015 at 8:17 pm (4 years ago)

    1st off let me thank everyone for sharing their experiences… My 15 year old Himalayan Serenity Has also been Diagnosed w/ Kidney disease and had all but quit eating and lost half his body weight My Vet Started Him on Renavast & k/d Diet Food and he has bounced back amazingly Eats small amounts 2 or 3 times a Day b/f dinner & then eats some more w/ his brother ( litter mate) I believe it has helped & and am continuing treatment … his Kidney Values Had Improved after he Had a 2 Day Stay w/ IV Treatment @ the Animal Hospital We will have his blood work rechecked come fall … We are Praying for improvement and a miracle…

  8. Mindy
    May 13, 2015 at 4:52 pm (4 years ago)

    It IS a scam. I read through the website before they were directed to remove the misleading information and the claims were outrageous. I subscribe to something called Quackwatch and the same kind of claims they show on quackery websites for humans applied to Renavast’s original website. I did however, ask my vet about it, and she consulted with the veterinary school in my state and they told her they thought it was nothing short of quackery, giving lots of reasons why that are beyond my comprehension….but think about this… their “study” involved a very small amount of cats. There was no real data given, it has not been written up in any veterinary journals, and there is no supplement like this on the market for human renal failure. Are the red flags going up?? Shame on the vets that are selling it for their own profits. Mine wouldn’t touch it. That means something to me. Of course people “think” it is working because they want it to work. Skept vet has a good article on this, he thinks it is fraudulent too.

    • Dawn
      May 17, 2015 at 6:01 pm (4 years ago)

      Hi Mindy,
      I have been using Renavast for over a year now, and my cats kidney values decreased and have now stabilized. Do I credit the Renavast? Its not the only thing I was doing at the time to help Snoopy, so I won’t say that it is a miracle cure.
      I did the research, I read the information and I was not completely impressed. Nobody should advertise their product as a miracle cure, and the maker’s of Renavast did imply that. But I am a smart consumer, I did my research and understood my choices. I will say that in all the research I did on it, nobody ever reported any harm to any animal, so I decided it was worth the money to try it. Since his numbers have decreased, then stabilized, I am satisfied. I will state that my brother had a cat diagnosed with kideny failure. He tried the Renavast, but within the month the kidneys went into complete failure and the cat passed away.
      Let other consumers do the research and make their own choice. Many medications we use to treat our pets end up causing us to add other medications because of side effects. Renavast did not have any that I read about or that I have identified while my boy has been on it. No complaints from this consumer.

      • Ingrid
        May 18, 2015 at 6:19 am (4 years ago)

        Thank you for sharing your experience with Renavast, Dawn.

  9. Josheph
    June 19, 2014 at 9:39 am (5 years ago)

    I found this website recently. Apparently it’s a tribute page for a cat named Maya. The cat-mom added all of this information about RenAvast. Where to buy (domestic and international) consumer reports, vet reports, etc. All the RenAvast ingredients are on there too. Check it out!
    http://renavast.wordpress.com/

  10. EcoPets
    June 7, 2014 at 12:32 am (5 years ago)

    I don’t think anyone claimed renavast was a wonder drug! I’d like to see that myself. I don’t think anything is a panacea! That would be impossible!

    As I mentioned formerly, Bio Health Solutions only submitted their manuscript for the renavast study in December 2013. How do I know this? I asked! Apparently, the manuscript gets submitted. Then the journal needs to find reviewers. Most reviewers are university professors that have a specialty in the filed in question. This isn’t a quick process. And the more respected journals take longer as they get bombarded with submissions. I have a vision of a professor with piles of journal articles strewn across their desk along with student papers to get graded among their other responsibilities. I am sure that once the study gets published, we all will hear about it.

    As for the FDA letter, they had a problem with what Bio Health Solutions detailed on the renavast website. If you compare the text from the FDA letter and the current text on renavast.com, it’s been totally edited. It seems to me that the FDA asked to remove the text, and Bio Health Solutions complied.

    Bayer received a similar letter from the FDA for marketing Baytril. Here is the link:
    http://www.fda.gov/downloads/AnimalVeterinary/GuidanceComplianceEnforcement/ComplianceEnforcement/ucm042458.pdf

    Would we not want to work with a company like Bayer either? Good luck with that!

  11. Joan P
    June 3, 2014 at 1:19 pm (5 years ago)

    Sorry…typo. What I meant is that no drug or product heals every individual. If that were the case people and animals would NOT die from heart disease, cancer, kidney failure, etc. No product works for 100% of people or animals. I am sorry your baby is not getting better. I feel very fortunate that mine is responding to RenAvast.

  12. Joan P
    June 3, 2014 at 1:09 pm (5 years ago)

    Caroline, How old is your cat? Have you ruled out an infection? What about hyperthyroid or hypertension? All of these issues can make CRF more difficult to treat. CRF is a progressive disease and keeps getting worse which is why so many of us are excited about levels that stabilize with RenAvast Of course no drug or supplement helps everyone. If that were the case humans and animals would die from heart disease, cancer, etc. Cats like humans are all individuals. I have friends who lived after chemo for breast cancer and I sadly lost a friend to breast cancer who did chemo. Cats and kidney failure are the same. But I would love to know about your cats age and other complicating factors. Also how much does she weigh? How much are you giving her? Also, don’t focus only on the numbers…if your cat is feeling good and eating that is great!

    • Josheph
      June 4, 2014 at 8:25 pm (5 years ago)

      So Joan: If my cat, or any cats for that matter, has high blood pressure, a thyroid problem or kidney infection how will renavast work? Will it work? Is there research that you can point me to related to chronic renal failure and any of these diseases. Fortunately, my vet takes my cat’s blood pressure and his is normal. He doesn’t like when it’s being taken because the equipment is so loud, but it doesn’t seem to increase his BP. It’s too early to check number for my cat, but so far his hair looks better and he seems more active.

      • Ingrid
        June 4, 2014 at 8:39 pm (5 years ago)

        Kidney damage can cause high blood pressure. Since RenAvast may help preserve or improve kidney function, it may also help prevent an increase in blood pressure due to kidney disease. Monitoring blood pressure should be standard care in monitoring kidney disease in cats.

      • Dawn
        January 6, 2015 at 1:11 am (5 years ago)

        Joseph,
        My 16 yo male cat has been on Renavast for about 8 months. He was diagnosed as hyperthyroid and is on methimazole to control it. Once the thyroid was under control, the kidney disease showed up in his bloodwork. My vet suggested renavast and after some research I decided to give it a try. So far, Snoopys kidney values have decreased with each bloodwork. Currently he is on the high side of normal. I know the renavast isn’t curing the disease, but it has allowed me to enjoy some stress free time with snoopy. I don’t give him subq fluids and know that snoopy will not handle having subqs as a part of his daily requirements, as I have difficulty giving him his Pepcid and methimazole.
        No research I did ever indicated it would be harmful, so I tried it. Am I positive the renavast is the reason for the changes in values? Not a hundred percent, but I am comfortable with the thought that I am doing what I can to keep him comfortable.

        • Ingrid
          January 6, 2015 at 7:09 am (5 years ago)

          Thank you for sharing your experience with Renavast, Dawn. Have you tried transdermal methimzole for Joseph? It’s easier to give for most cats than the oral version. I’m not sure whether Pepcid can be compounded into a transdermal version, but it can’t hurt to ask.

          • Dawn
            January 6, 2015 at 7:19 am (5 years ago)

            I have tried transdermal on Snoopy. im not a big fan and prefer not to try that route again. It sounds simple and like a great solution, but it wasn’t for me. Snoopy began to hate having me come near him because he didn’t like me rubbing something in his ear, plus you have to ensure that all of the old stuff is removed from the ear, so I had to clean his ears everyday as well as giving him the medicine. On after monitoring his blood levels a few times, we determined that not enough methimazole was getting absorbed to properly counteract the hyperthyroid.
            As for the Pepcid, I won’t try compounding that for the reasons I just gave. I give him Pepcid to help counteract the acids in his stomach caused by the kidney failure. My CKD research showed me that it helps, and I know for snoopy that it does. Serious decrease in vomiting of clear fluids with a pink tinge, which was occurring everyday.

  13. Caroline
    June 2, 2014 at 7:27 pm (5 years ago)

    My kitty has been taking RenAvast for 8 months now and all her levels have gone up. Somewhat significantly.

    It’s just such a kick in the heart.

  14. Josheph
    May 31, 2014 at 10:51 pm (5 years ago)

    Thanks Mariah! Really can tell that you care.

    Has anyone confronted Bio Health Solutions about any of this. I, for one, would like to hear from them.

    As far as I know, renavast is a supplement; not a drug. As far as “wonder”, I’m still waiting to find out.

    In April, Ecopets addressed a few of these questions. According to them, the manuscript behind renavast was only submitted to a journal for peer review in Dec. 2013. Does anyone know how long it takes to get a study accepted? Apparently, the peer review process is a slow process. Could it be possible that the study hasn’t been accepted yet?

    I definitely had the same questions about the FDA letter. On that same April comment, here is what they said: “As for the FDA letter, many large companies receive the same letter for their products. Baytril, Prilosec, Tramadol and Flagyl have all received similar letters to the one that RenAvast received. Dannon yogurt received a similar letter. They are all on the internet as well. These products, minus the yogurt of course, are commonly used in veterinary medicine.”

    I found the FDA letters that this person mentions, and they were very similar. And my vet just put my cat on Flagyl (he didn’t like the taste though).

    I then went to renavast.com and noticed that all of the items that the FDA mentioned were no longer on the website. The FDA letter said basically to change your website, and it looks like they complied.

    The FDA letter appeared to be about marketing. As far as I can see the company doesn’t market renavast. They have a bunch of veterinary supply companies, both domestic and international, listed on their renavast site that appear to be responsible for distributing renavast to vets and pharmacies. These are huge respectable companies. I’d be surprised if they would work with a less than reputable organization.

    Also, is it possible that people who work for Bio Health Solutions use their own products? The guy that Mariah mentions as the CEO is on linkedin and isn’t a CEO by any means. Just some employee.

    His wife, on the other hand, is some high profile animal person who ran the New Orleans rescue for the HSUS. I googled her and she apparently authored a book on elephants and ethics.

    Unfortunately the internet is a festering petri dish of misinformation. I basically don’t trust anyone or anything that I read. Especially hearsay!

    I love the comradery on this site and look forward to more friendships to develop.

  15. Mariah
    May 31, 2014 at 9:33 pm (5 years ago)

    If this is such a “wonder drug” or solution where are the write ups in veterinary journals?

    The FDA letter should not be ignored, it points out several false claims that the manufacturer was making and they were told to take this information off their website. I think that is pretty significant and I think everyone who is considering giving this to their pet should read that letter. I certainly would want nothing to do with a company like this.

    And something else that I became aware of is since I first posted is that several of the cats out of the 19 in the study belonged to the CEO and employees. Both the CEO and his wife were posting on forums and even Amazon (under their real names) pushing the product.

  16. Josheph
    May 24, 2014 at 4:35 pm (5 years ago)

    So for Mariah and others that are having trouble finding the ingredients, here are all the links. The ingredients are everywhere. Also, I did a PubMed search and there are ~70,000 studies with 19 subjects or less. Correct me if I am wrong, but doesn’t the peer review process determine if the science is sound or not? And if they are cited on PubMed, they have met the rigors of this scrutiny. I’m more comfortable with academic journals determining what science is as opposed to the random opinions of those on blogs or chat rooms.

    Comment edited by blog owner to remove multiple links. Product label provided below.

    Product label:

    RENAVAST™ (CATS AND DOGS) – under 20lbs

    Bio Health Solutions

    promotes heathy kidney function

    SUPPLEMENT FACTS

    Serving size: 1 capsule

    Serving per container: 60

    Amount per Serving

    %RDV

    Amino Acid and Peptide Proprietary Blend 300mg

    **

    L-Aspartic acid, L-Carnosine, L-Glutamic acid, L-Glutamine, Glycine, L-Arginine, L-Histidine.

    Other ingredients: Maltodextrin, gelatin from capsules, magnesium stearate and stearic acid.

    **Percentage daily values are not established.

    *DIRECTIONS:

    • Mix the capsule contents with a small amount (i.e. tablespoon) of wet food to ensure that your cat or dog eats the entire amount.

    • Cats or dogs under 10 pounds – 1 capsule mixed with food twice daily. Cats or dogs 10-20 pounds – 2 capsules mixed with food twice daily.

  17. Pat
    May 23, 2014 at 5:19 pm (5 years ago)

    I don’t know anything about a treat but my cat acts like it already IS a treat. She sits on the counter practically begging for her syringe full of water and Renavast powder. So funny! She trained me to do that. I used to put it in her food, then into some baby food, and now we just do the syringe. She’s my little crazy lady LOL.

  18. Joan P
    May 23, 2014 at 11:16 am (5 years ago)

    Not sure if they are doing a treat. I am happy with the powder so does not really matter to me. I know that my friend with a dog on RenAvast puts the whole cap in some peanut butter and the dog eats the entire cap of RenAvast…certainly can’t do THAT with a cat!

  19. Josheph
    May 21, 2014 at 4:43 pm (5 years ago)

    Little Joe isn’t having a problem with eating, which makes the RenAvast easy to dose. It’s too bad that I can’t just put the Azodyl on the food as well. That’s okay since he is easy to pill. My vet’s tech showed me how and LJ was a champ. I guess I’m fortunate in that regard. Funny thing happened though. When I got the RenAvast, I opened the capsule and put it on the plate. I turned to get the wet food and noticed he was eating the powder off of the plate. As I said, LJ never has a problem eating. It’d be great if they made it in a treat. He loves that stuff. Does the company have any plans? I won’t change the food then. Thanks guys! Joe

  20. Joan P
    May 21, 2014 at 2:17 pm (5 years ago)

    I feed my babies all wet food…no dry. Cats get 75% of their water intake from food so stay away form dry food if possible. I don’t think the food you feed matter with the effectiveness of RenAvast. I am on a facebook CRF group and most people on there use RenAvast and everyone feeds something different. Most important thing is that your animal is eating…not what they eat. The good news is that RenAvast increases appetites for animals with CRF (chronic renal failure).

    • Pat
      May 21, 2014 at 5:49 pm (5 years ago)

      So true, Joan!! I switched my kitties to an all wet food diet years ago and I feel terrible that I didn’t know about that sooner! Although there are different causes of kidney disease, there seems to be a growing consensus that the dry food is causing a lot of it. My first furry child died of renal failure in 2004 and I suspect it’s because I only ever fed her dry food. I just didn’t know any better. 🙁 So now my kitties get a good quality canned food most days, with occasional treats of junk food, but ALWAYS wet.

      Joe: I have heard only good things about a raw diet but haven’t looked into it that much. You should be able to give the renavast and azodyl with either type of food. The Renavast is so easy, even if your cat is not eating much you can just mix the powder with a little bit of water and use a syringe to slowly feed it to her.

  21. Joseph
    May 16, 2014 at 11:57 pm (5 years ago)

    I don’t know about the rabbits. I would definitely get with the renavast people about that. Their website talks about cats and dogs only. I’d want to make sure. On another note, I read elsewhere that I should consider a raw diet for little Joe. Does anyone have any experience or knowledge on this? My vet doesn’t have an opinion either way. How would that type of diet impact the renavast and the azodyl? Thanks!

  22. Joan P
    May 14, 2014 at 1:20 pm (5 years ago)

    Does anyone know if RenAvast can be used for rabbits with chronic renal failure (CRF)? A friend asked and I had no idea. I may just email the customer service. I think their contact is on their web site at http://www.renavast.com. But if you know please let me know. Thanks!

  23. Joseph
    May 12, 2014 at 3:25 pm (5 years ago)

    Caroline: Bio Health Solutions is only an R&D firm. They have no sales or marketing efforts. Your best bet for RenAvast is either your vet or one of the online pharmacies.

  24. Joan P
    May 6, 2014 at 9:25 am (5 years ago)

    I have been using RenAvast for a few years. I used to buy it form Bio Health Solutions but now I buy it from my vet. Although I do watch for the sales on the online pharmacies….often RenAvast is cheaper. I have used Azodyl with RenAvast by suggestion of my vet. However, RenAvast is so much easier to give that I asked my vet if I could stop Azodyl. Since my cat is doing so well on RenAvast I no longer give Azodyl. By the way…I am so thankful to my vet for putting my baby on RenAvast…chronic renal failure would have killed her if not for this amazing product!

    • Caroline
      May 6, 2014 at 8:44 pm (5 years ago)

      I get my RenAvast from Vet RX Direct. I will check out Bio Health Solutions to see if it is more economical. I use both RenAvast and Azodyl.

  25. Joseph
    May 3, 2014 at 9:50 pm (5 years ago)

    I have been suspicious as well. However, I’m noticing a lot of positive feedback about RenAvast for CRF kitties. My vet has recommended it for my cat. There are a lot of online pharmacies making it available. And I don’t see anything that indicates that Bio Health Solutions is actually selling it. As a matter of fact, I tried to buy it direct and they directed me back to my vet. Can I use RenAvast with Azodyl?

    • Ingrid
      May 4, 2014 at 5:22 am (5 years ago)

      You will have to check with your vet about whether RenAvast can be used with Azodyl, Joseph.

    • Pat
      May 6, 2014 at 3:05 pm (5 years ago)

      The ingredients are on the bottle and you can find them if you search around online. For example, they are listed at this seller’s site: http://www.heartlandvetsupply.com/p-4690-renavast-sprinkle-capsules.aspx. They’re right there on the label. When I first started using Renavast, I called the company that makes it and asked my questions. They were really helpful. They told me Renavast can be used with other medicines with no problem but I would still ask your vet what’s right for your cat.

  26. Carol
    March 26, 2014 at 5:25 pm (6 years ago)

    My dog, Chelsea, was diagnosed with renal failure this past September. The vet said she was in “moderate” kidney failure, but she acted much sicker than that. I tried giving her subQ fluids, but she wasn’t cooperative. I had given Renavast to our 22 1/2 yr old kitty, Misty for over a year, and while she was on it, her kidney values improved and stayed stable… BUN in mid 30’s and Creatinine in mid 2’s. That was down from BUN being in the high 70’s and Creatinine in mid 4’s. I think that’s a great improvement. So I decided to try it on Chelsea. She’s been on it since September 2013 and aside from still drinking a bit more water than what I’d say is normal, she’s feeling good, playing, eating, tail wagging… all in all she feels pretty good. We haven’t gone back for bloodwork recently, finances prohibit it, but I can tell from the way she feels that she’s probably got better kidney values than before. When we do take her in for repeat labs, I’ll come back and post her numbers.

    • Ingrid
      March 26, 2014 at 5:29 pm (6 years ago)

      Thanks for sharing your experience with RenAvast, Carol. I’m glad to hear that Chelsea is doing so well!

  27. Mariah
    January 23, 2014 at 3:37 pm (6 years ago)

    My vet thinks this is “snake oil” for the reasons above, the refusal to release the ingredients, the weak “study” with 19 cats, no veterinary journal write ups, etc.

    After I saw this letter on the FDA’s website I am convinced that this is just another scam company trying to make a buck off desperate pet owners. We all know about placebos and if you look at any drug study you will see that placebo control groups showed improvement and or had side effects.

    http://www.fda.gov/ICECI/EnforcementActions/WarningLetters/2012/ucm325700.htm

    • Ingrid
      January 23, 2014 at 4:01 pm (6 years ago)

      I won’t comment on the FDA letter – this gets into the whole issue of oversight and classification of drugs, supplements, and the associated politics, which is not relevant to this topic.

      There will always be veterinarians and physicians who will not be open to supplements and similar products because they feel that there weren’t sufficient studies, or that the studies were not sufficiently rigorous. I believe that it’s up to each pet guardian to make an informed decision, based on the information available, and that decision process should include a discussion with their veterinarian. To me, the anecdotal evidence is pretty compelling.

    • Ecopets
      April 12, 2014 at 4:40 pm (6 years ago)

      It is odd that anyone is having a challenge getting the ingredients. The ingredients are on the label. All a vet needs to do is contact their veterinary supply sales rep at Henry Schein, Patterson, MWI, Miller, Merritt or Penn vet supply and they can get all the information that they need. No mysteries. The ingredients have been available. The rumor that this is hidden is absurd. Has no one thought to ask the company?

      The manuscript for the study has only been submitted for peer review in December 2013. Once accepted, anyone can get a copy from a PubMed search. Sales reps at the above companies will be getting copies to their vet clients upon acceptance. It is suspicious that anyone should comment on the study when the journal, nor the company, has made it available to the public. Only the academics that are charged with reviewing the article will properly judge the science behind the study. That’s why we have a peer review process.

      As for the FDA letter, many large companies receive the same letter for their products. Baytril, Prilosec, Tramadol and Flagyl have all received similar letters to the one that RenAvast received. Dannon yogurt received a similar letter. They are all on the internet as well. These products, minus the yogurt of course, are commonly used in veterinary medicine. I don’t think they’d be considered snake oil. And certainly they are not taking advantage of consumers.

      Hope this clarifies.

  28. Christine 7off
    January 8, 2014 at 8:22 pm (6 years ago)

    hello and thank you so much for all your great comments I really appreciate your feedback. I just had one last question I received the renavast I ordered today and I’m mixing it with food as instructed but I have another cat the same age that does not have kidney issues so what if she accidentally eats the food that has this medicine in it. will it hurt her? or do I need to have strict eating quarters for both cats when I put out there wet food.
    Also, have you heard about the cat food wet and dry called Hi tor Neo vet formula in wet food and Felo dry cat?
    Thank you again

    • Caroline
      January 18, 2014 at 1:09 pm (6 years ago)

      Hi Christine,

      I spread some baby food on a plate and put the RenAvast right on top of it. No need to cover it up with more food (and that is hard to do) My cat licks the plate clean. I put the RenAvast in the middle and the surrounding edges are just plain baby food.

      Place the small plate in front of the kitty that needs the medication. You could also use a syringe, with food, as well. That info is in a comment above.

  29. Christine 7off
    January 8, 2014 at 10:25 am (6 years ago)

    Thank you Ingrid for your response. My cat did not have elevated calium levels prior to starting calcitrol and had slighly elevated bun and creatine and little anemia. Now after going to the vet several times to adjust these meds the calcium is back to normal and bun and creatine are still a little elevated as before she started so I don’t see big improvement from the meds. She’s still not eating like she should but she does have energy like she did. She used to be a 12 lb cat and is now 7 1\2 lbs. She licks the gravy from wets food, so I’ve started making cats smoothies with her renal wet food which she likes with a little wellness chicken for flavor. She eats some crunchy food after trying every prescription food that she hated, I found s\d mature 7 plus indoor cat food that she will eat that is lower protein and decent phos levels. I’ve also just odered Hi Tor Neo wet and dry just for her to sample to see if she gobbles it up like some of the reviews I’ve read. Since she’s not eating much how would I even give her 2 doses of renavast like it mnetions to do? I’m willing to try both. Thank u

    • Ingrid
      January 8, 2014 at 10:41 am (6 years ago)

      I know it’s challenging to get cats in renal failure to eat, Christine, especially since the low protein diets are generally not very palatable . Some vets are changing their thinking on protein restriction in cat with renal failure, this article explains more about that: http://consciouscat.net/2011/10/17/kidney-failure-and-diet-in-cats/

      You can try mixing the supplement in with a little bit of tuna juice or clam juice – some cats seem to like it. I’m guessing that you’re not able to pill her? If you can, you can put the powder into clear gel caps (available from most pharmacies).

      • Jo
        February 17, 2014 at 9:54 am (6 years ago)

        Baby food meat (check ingredients for no onion powder) makes a great treat in which to mix meds and supplements, as well. I use Gerber’s as it seems to be the most palatable to my cats. Just a small spoonful does the trick and it is relatively low in phosphorous–well below 1% on a dry matter basis the last time I checked.

  30. Christine 7off
    January 7, 2014 at 8:20 pm (6 years ago)

    hello my 14 year old cat was recently diagnosed with moderate kidney failure and she has been put on medication called Calcitrol at .3ml daily. we had to adjust her meds as for calcium levels spiked up so this level seems to have brought her calcium level ba.ck to normal which is great. her energy level seems somewhat back to normal and she’s eating but not as much as I would like her to eat and would like to see her gain a few pounds back, so o I thought about starting her on this medication renavast in addition. But are there any known side effects or would you suggest I wait to if any improvement on her weight and appetite? My vet said it was ok for both but why give her both when I already struggle with giving once a day meds of calcitrol. Maybe this calcitrol isn’t working as good as I thought or should I see results in a few more weeks or months

    • Ingrid
      January 8, 2014 at 6:56 am (6 years ago)

      It sounds like the Calcitrol is working, Christine, if her calcium levels are back to normal. There are never any guarantees with any supplement, but given the results reported from RenAvast, and since your vet says it’s okay to give together with Calcitrol, it sure sounds like it would be worth a try.

  31. Caroline
    December 2, 2013 at 1:46 pm (6 years ago)

    My kitty was diagnosed with kidney disease a month ago. I have been using RenAvast and Azodyl for one month. Her BUN has dropped, but not her Creatinine, which is a more accurate measurement of kidney disease as it is less affected by diet and dehydration. It is a shame, as my kitty has always eaten high quality wet food, had plenty of water and her teeth brushed regularly. Yet she has it. And I never over vaccinated her. Only kitten vaccinations. But I will do my best for her.

    • Anjali
      December 2, 2013 at 1:49 pm (6 years ago)

      Sorry about your kitty’s kidney disease. I have two senior kitties with kidney disease and my vet has them on a low dose of Calcitriol. One kitty, Luna, is on 0.25/mL daily and her BUN and Creatinine levels have fallen back into the normal range after several weeks of treatment and adjustment of her dose. Maybe ask your vet about Calcitriol? I understand that phosphorus levels need to be monitored every few weeks for a while and then only every few months. I am not a vet, so I can’t recommend anything, but the Calcitriol has dramatically helped one of our two senior cats and has kept the other kitty stable.

      • Caroline
        December 2, 2013 at 2:28 pm (6 years ago)

        Thank you. I will look into this right away. My kitty is also a senior at 14 1/2.

        • Anjali
          December 2, 2013 at 2:30 pm (6 years ago)

          That’s exactly the age of my Luna. On a very tiny dose of Calcitriol, her kidney values have fallen back into the normal range. Dramatic! But vet monitors blood values. At first it was every few weeks… now it’s every few months.

          • Caroline
            December 2, 2013 at 2:43 pm (6 years ago)

            I am happy your kitty is doing so well! My kitty’s BUN came down to 37, but her Creatinine is still 3.3. Are you also taking RenAvast or using Azodyl? Thanks. I am excited to know about Calcitriol.

      • Caroline
        December 2, 2013 at 2:29 pm (6 years ago)

        Thank you.

    • Jo
      February 17, 2014 at 9:48 am (6 years ago)

      Caroline, I would strongly recommend you continue using the Renavast and Azodyl on your kitty, even though her creatinine has not come down! Keeping BUN in the normal range is also critically important to a cat in renal failure and will go a long way towards keeping cats comfortable, eating well, not vomiting, etc. If those two products have brought her BUN down, that is wonderful news in itself; I would not rock the boat!

  32. Dean
    October 21, 2013 at 3:31 pm (6 years ago)

    I work at a natural pet food store and we carry the Renavast product. Almost without exception cats and dogs improve while using the product. The improvements reported are in the general disposition of the animals…more energy and alertness, improved appetite as well as the ability to gain weight. The customers that have had follow up blood work done also report improvements in BUN & creatinine. While I know this is only anecdotal evidence, it does carry some credence.

    Unfortunately most people are not aware of what causes most renal failure in the first place and that is feeding food, more commonly known as kibble. Kibble is very highly processed and no matter how much you pay for it the protein quality is compromised from high temps in the manufacture of the food. For cats it’s especially bad because they have such a low thirst instinct. Once the symptoms show up it’s too late and the damage is done. Feeding a canned or raw diet with low carbs and low ash will go a long way towards preventing, as well as treating the animals.

    • Ingrid
      October 21, 2013 at 4:13 pm (6 years ago)

      Thank you for sharing your customers’ experience with Renavast, Dean. You’re absolutely right, cats should never eat dry food.

  33. wendy
    September 18, 2013 at 3:02 pm (6 years ago)

    I started my 15 year old cat Joey on Renavast after his blood results showed creatinine and BUN were high. 6 months later we did another blood test and his creatinine was on the high side of normal and his BUN had dropped 10 points but was still on the high side of normal. But both are now in the normal range.
    Joey has been a very picky eater for years and now eats all his food. He is active, alert, playful and seems happier. I will continue with Renavast and re-do blood in another month or two (this will be 10 months on Renavast).
    I am happy with the product and as long as there are no drugs involved…just enzymes and peptides I will continue with it.

    • Ingrid
      September 18, 2013 at 5:58 pm (6 years ago)

      Thanks for sharing your experience with Renavast, Wendy. I’m glad it’s working so well for Joey!

    • Jo
      February 17, 2014 at 9:42 am (6 years ago)

      Wendy, did you retest your cat’s blood since your last post? What were the results?

      • Wendy
        April 26, 2014 at 6:05 am (5 years ago)

        His last blood test after being on Renavast for over 1 year…creantinine had jumped from 4.2 to 4.6 but the BUN went back to the normal range. All other values are normal. He is still eating well and seems happy so I will continue to use it for now.

  34. Maxwell, Faraday & Allie
    April 22, 2013 at 10:34 pm (6 years ago)

    Interesting. And most interesting were their answers in the comments. Hoping this helps many CRF cats!

  35. Anjali
    April 22, 2013 at 9:35 pm (6 years ago)

    Interesting – thanks for posting. It’s always good to know about new options for treatment, but I agree with Ruth. A study of 19 cats is pretty small. I will wait for more definitive data.

    Two of our five cats are seniors with chronic renal failure. They’re both on a Calcitriol supplement, which has much more extensive data to support its use. One of our two cats, Cheyenne, stopped peeing outside the litterbox after a few weeks on Calcitriol. She had been peeing on rugs, the floor, and in various other places for years. She’s been on the Calcitriol for a few months now, and while her BUN and Creatinine levels have come down only slightly (they have not risen), her behavior has improved dramatically. In addition to her improved urination habits, she is as lively and playful as a kitten. She is 15 years old. Luna, our other cat in renal failure, has only been on the supplement a few weeks and her kidney levels are stable. Cats on Calcitriol do need to have phosphorus levels checked periodically. I get tuna-flavored liquid from the compounding pharmacy.

    • Ingrid
      April 23, 2013 at 6:43 am (6 years ago)

      I have heard good things about Calcitriol, Anjali.

    • Jo
      February 17, 2014 at 9:40 am (6 years ago)

      Anjali, your post is very interesting. My understanding of calcitriol is that it is used solely to treat low blood calcium. That is based on my research of articles and posts by Dr. Larry Nagode at UC Davis Veterinary School who appears to be an expert on the use of this drug in cats.

      Did your vet put your cats on calcitriol because they had low calcium, or is he using it to treat chronic kidney disease in general? I would sure like to know. If the latter, I would like to investigate that possibility with my own vet! Thanks!

      • Jo
        February 17, 2014 at 3:48 pm (6 years ago)

        My apologies for the above error…Dr. Nagode is with Ohio State U, not UC Davis. I had another doctor in mind when I wrote that!

        In addition, you can find a lot of good info about the use of calcitriol in cats with CKD on felinecrf.org.

  36. Bernadette
    April 22, 2013 at 8:40 pm (6 years ago)

    I’m so glad to see this is successful! It sounded so promising that when the testing began I contacted them about including Peaches, who was 20 and in kidney failure but doing well, in the testing. The only reason we didn’t was the testing required monthly blood tests and Peaches was only five pounds and on the anemic side; my veterinarian and the person I spoke with decided it might be a bit much for her. I’ve kept an eye on it and it wasn’t quite ready for Cookie last year. I hope I’m years away from any renal failure but if it does happen I’m keeping this in mind.

    • Bernadette
      April 23, 2013 at 12:41 pm (6 years ago)

      Oops, that was a 2010 study of mirtazapine, sorry!

  37. monica ackerman
    April 22, 2013 at 7:49 pm (6 years ago)

    This sounds fantastic. I definitely would have tried it on my Maxximus who died after a period of less than 3 months of some undiagnosed fast-moving illness. He was checked by the vet end of May when he was there for his booster shot and died Labor Day weekend wen I was not home. In retrospect we suspect he might have had renal failure but his other symptoms pointed to a brain tumor so we can’t be sure. I couldn’t afford a necropsy since they charged me $195 for private cemation and an urn. Taking him to the vet always had been so traumatic for him and me and the vet that I thought twice about bringing him back. He seemed to age so quickly and he lost his cognitive functions which made me think of a brain tumor. He always had to be sedated to let the vet handle him and I didn’t want to do that to him unless absolutely necessary. We should appreciate all the research in the scientific community which helps our kitties. I have two very healthy kitties and look forward to a long life with them. Thanks, RenAvadst for all you do.

    • Ingrid
      April 23, 2013 at 6:44 am (6 years ago)

      I’m sorry about Maxximus, Monica.

  38. RenAvast
    April 22, 2013 at 1:57 pm (6 years ago)

    Thank you for such a great blog on our product.If anyone has any specific questions or concerns we are always available at customerservice@renavast.com.
    Ruth, the following are answers to your concerns. As far as the complete ingredient list, that will be released very soon now that the patent application is pending. The company could not release the details until the formula was protected.

    Answers to your questions:

    Are nineteen cats in a study enough?

    Yes. Many scientific studies are done with fewer subjects and over shorter time periods. In
    fact, there are thousands of human studies in peer reviewed journals with less than 19 patients. Nineteen patients in a study is acceptable; not to mention the fact that there are numerous over-the-counter medications used to treat humans and animals that are not based on any studies, peer reviewed or otherwise, with only subjective and anecdotal evidence as proof of efficacy. An interesting aspect of the RenAvast™ study is that blood chemistry measurements identified a physiologic change over the patients’ former test findings. In addition, nineteen cats are nearly three times the number of cats used in the study for the number one and most often prescribed (by veterinarians only) product to help reduce BUN in cats and dogs.

    Why was there no separate control group?

    In this particular case, a separate control group was uncalled for and would not have yielded useful information. The outcome of untreated chronic renal failure is already known: biochemical and hematological blood serum values deteriorate over time. The study was structured in the same way that many medical studies are modeled when a separate control group is not feasible, practical, ethical or necessary.

    The study that you may have read Ruth is a “ghost version” of the actual study. When studies are being submitted for peer review, as RenAvast is, we can only allow the public to read part of the study otherwise the study would be disqualified. We believe you will be thrilled once you see the final manuscript. In addition, over 1,000,000 meals with RenAvast in it have been given to cats with unbelievable feedback from their vets or cat parents. We are very proud of this product and are excited about the dog version soon to be released. Please do not hesitate to email us if you or anyone else has any questions or concerns. Thank you!

    • Ingrid
      April 22, 2013 at 3:55 pm (6 years ago)

      Thank you for addressing the questions!

  39. Avarie Shevin
    April 22, 2013 at 1:31 pm (6 years ago)

    I just recently started using RenaVast and am so happy I did! Years ago I had a cat die from renal failure and I didn’t have RenaVast. Luckily I caught it very early in my current cat Rose and everyone I have spoken with has just raved about RenaVast and how it has prolonged the life of their cats with renal failure. It is very easy to use — I just put a little in an oral syringe with food and water and she let’s me give it to her easily twice a day. The customer service department is also a real pleasure to deal with!!! I’m a very happy cat mommy and RenaVast customer.

    • Ingrid
      April 22, 2013 at 3:54 pm (6 years ago)

      Thanks for sharing your experience, Avarie. I’m so glad Rose is doing so well.

  40. Laura K
    April 22, 2013 at 11:10 am (6 years ago)

    We have an almost 15 year old cat in CRF who also has high blood pressure & pancreatitis. I’m tempted to order this if it would help give him better quality of life. I am asking my own vet to look in to the product himself though, but I do like that Ingrids vet is currently using the product with some success.

    • Ingrid
      April 22, 2013 at 1:27 pm (6 years ago)

      Let me know what your vet says, and whether you decide to use the product, Laura.

      • Laura K
        April 22, 2013 at 4:13 pm (6 years ago)

        I actually texted them the info & he felt that there wasn’t enough info & he hadn’t used it before–however he did feel it was worth a shot trying it.

        • Ingrid
          April 23, 2013 at 6:45 am (6 years ago)

          Let us know how your kitty does on it, Laura.

  41. Amanda
    April 22, 2013 at 10:43 am (7 years ago)

    I LOVE this product!!! My 15 year old cat has been on it for 6 months. Boy, RenAvast has certainly given him a better life already!! He is sleeping less, gained weight, and is overall a happier boy. I highly recommend it and am so glad our vet said to give it a try.

    • Ingrid
      April 22, 2013 at 1:26 pm (6 years ago)

      Thanks for the feedback, Amanda. I’m so glad to hear the product is working for your boy!

    • Jo
      February 17, 2014 at 9:20 am (6 years ago)

      Have you had your cat’s blood tested since starting this? What were the changes if any to his kidney values?

  42. mikken
    April 22, 2013 at 10:19 am (7 years ago)

    Their data does seem a bit…sparse. And one hopes that the product is at least harmless, if nothing else. But it is concerning how little information they actually give you…that may be the result of trying to be proprietary or it may be something else, I don’t know.

    But right now, I have a cat with ‘issues’ (we’re at a diagnostic wall because he cannot be safely anesthetized) and one of his issues is apparently having one kidney working overtime to compensate for some kind of failure in the other. It’s not CRF per se, but it’s part of whatever package he’s got happening and it clearly affects him.

    So I will try it. What the heck, why not, right? And I’m sure that people dealing with CRF/CRI will want to try it, too because you get to a point where you have nothing to lose by trying and any hope is welcome. If it helps, it’s a blessing. If it’s a scam preying on the desperate, it’s criminal. Time will tell.

    • Ruth
      April 22, 2013 at 10:29 am (7 years ago)

      Point, and if the vet had suggested it when my Janie was still alive I have to admit that I might have tried it out of desperation. I just really wish they gave more info on the ingredients at least, that would make evaluating it far easier.

      • Ingrid
        April 22, 2013 at 1:26 pm (6 years ago)

        I, too, would prefer to see the list of ingredients, Ruth. And in all cases, I would always recommend checking with your vet before putting your cat on any supplement.

  43. Sue Brandes
    April 22, 2013 at 10:11 am (7 years ago)

    Sounds promising to me. Hope it helps your kitty.

  44. Ruth
    April 22, 2013 at 9:49 am (7 years ago)

    Their study has some problems that I’d consider less than delightfull.

    Cats in this study came and went, with no apparent followup, and it was ONLY 19 cats, which really isn’t that large of a group. Though none of the cats were on fluids or a prescription diet there’s no data on whether the cats were on other treatments. There was no control group. You’ll notice that their claim is that the cats in the study showed improvement or “didn’t deteriorate”, and if you actually read the study most of the improvements are NOT large, and are infact not out of line for a cat NOT being treated with Renavast, but under a controlled diet and vet supervision in the early stages of kidney failure, which it appears all these cats were.

    Plus they won’t release their ingredient list.

    I doubt that Renavast would HURT, but I’d want a more comprehensive study before I’d give it to my animals.

    • Jo
      February 17, 2014 at 9:17 am (6 years ago)

      Agreed! I’d be skeptical of any company that refused to tell consumers the ingredients in their product. Buyers deserve to know what they are paying for, especially on health related products they or their animals are consuming!

  45. Gail W.
    April 22, 2013 at 9:37 am (7 years ago)

    I wish this had been available when my late cat, Thomas, was still with me. He passed from a combination of renal failure and restrictive cardiomyopathy. I would have tried it.

    • Murray Cat
      January 18, 2014 at 9:34 am (6 years ago)

      16 yr old Murray Cat has been on Science KD for 5 years for mild CRF but in the past few months, had significant weight loss. Blood test showed severe anemia and high Bun & Creatine. Vet started him on RenAvast daily mixed in his KD (or HiTor Neo) canned food (he isn’t a fan of either so have to mix in a little regular can food) as well as IV Ringers 3x a week. Mild mannered Murray has been a trooper – no complaints about me sticking him with a needle. It’s only been a month,he hasn’t gained any weight, but his blood test shows improvement. IV reduced to 2x /week. Will keep on this regime and test him again in 2 months.

      • Jo
        February 17, 2014 at 9:30 am (6 years ago)

        Murray Cat, PLEASE report back to this blog once you have your cat’s blood tested again and let us know what changes if any occurred to your cat’s kidney values! Although, the addition of subQ fluids alone will undoubtedly have a very positive effect on his values. I’ve had cats all my life and have cared for many with CKD. In my experience, giving fluids is the single best thing you can do for a cat with failing kidneys to prolong their life by years and keep them comfortable. The improvement seen is profound!

    • Elizabeth
      April 26, 2014 at 12:05 am (5 years ago)

      Not sure how to leave a comment so I am leaving a “reply” here.

      I have a 14 year-old female cat that was just diagnosed as having CRF. She is at the end of the beginning stage of the disease according to my vet. The vet I am now bringing my cat to does wholistic veterinarian treatment of cats. She had a CRF cat die of the disease that had been treated with the traditional allopathic veterinarian methods (KD, etc.) After that she decided to go into the alternative treatment side of vet medicine. So, she is the one who suggested the Renovast, citing the Renovast study and the positive results. My cat’s bloodwork has shown fairly unremarkable results right now, with some mild abnormalities related to the CRF disease, but her urine is very dilute, she urinates a lot, and she’s drinking lots of water. She is very finicky about eating the wet foods (KD or not, and mostly natural cat foods) since she ate regular store-bought pellets for years. This has been really stressful for me, to get her to eat. My current vet does not think it is so beneficial to use KD foods due to a cat’s natural need for plenty of protein. Plus my cat doesn’t like KD wet foods anyways. May have to go to some other less wholistic canned foods or something to get her to eat. Am trying low-sodium (70mg/cup) chicken broth soaked pellets, KD or not, will see how she does. I give her and my dog R/O filtered drinking water. However, the vet told me raw goat milk is ok for her. So, I dissolve 1/8 tsp potassium (Renal K) (vet prescription) and one cap of Renavast powder in a small amt. of slightly warmed goat milk with a couple light drops of salmon oil in it 2x daily (the Renavast 1, 1x daily). She laps this up readily, thankfully. Just started this routine in addition to whatever solid foods she’ll nibble at. She had been eating “gourmet” pills: Standard Process Renal Support tablets wrapped in pill pockets rolled in tasty liver powder, but now she turns her nose up at even this, as she won’t eat the SP tablets by themselves. I do give her the Vetri-Science Renal Essence chewable tablets (since I stopped the SP tablets as she doesn’t like them now, I have been giving her 2 V-S Renal Ess. tabs 2x daily and she likes those, usually anyways.) Will have to keep you posted on her progress.

      • Elizabeth
        April 26, 2014 at 12:30 am (5 years ago)

        Sorry, I misspelled Renavast a few times in my post!