By Dr. Karen Becker

I often write about the uniqueness of felines. Your kitty is not only very different from dogs – she stands apart from most other species.

Her physiology is distinctive. Her nutritional requirements are unique among mammals. Even the way her body is constructed – her incredible physical flexibility – is distinct from most other creatures.

Another thing that is very unusual about our kitty companions is their tendency to develop a weird disorder called feline hyperesthesia. This is a medical term for what is more commonly referred to as “rippling skin syndrome,” “rolling skin syndrome,” or “twitchy cat syndrome.” Other technical names for the condition include neuritis and atypical neurodermatitis.

Signs and Symptoms of Feline Hyperesthesia

The word hyperesthesia means “abnormally increased sensitivity of the skin.” It’s a condition in which the skin on a cat’s back ripples from the shoulders all the way to the tail. The rippling is visible in some cats, but more difficult to see with others. What many pet owners notice first is the kitty turning toward her tail suddenly as though something back there is bothering her. She may try to lick or bite at the area. And most cats with this condition will take off running out of the blue as though something scared them or is chasing them. Kitties with hyperesthesia also have muscle spasms and twitches, and twitching of the tail.

If your cat has the syndrome, he may show sensitivity when any point along his spine or back is touched. He may chase his tail, bite at himself, turn toward his tail and hiss, vocalize, run and jump. He may also seem to be hallucinating – following the movement of things that are not there – and he may have dilated pupils during these episodes.

In severe cases of feline hyperesthesia, cats will self-mutilate by biting, licking, chewing and pulling out hair. These poor kitties suffer not only hair loss, but often severe skin lesions from trying too aggressively to seek relief from the uncomfortable sensations they experience.

Causes of “Twitchy Cat Syndrome”

No one knows for sure what causes hyperesthesia in cats, but one of the first things you should do if your kitty is having symptoms is to rule out other causes for itching and twitching.

It’s important to investigate flea allergy dermatitis (FAD) as a cause or contributor to your cat’s behavior. In pets with a severe flea allergy, the bite from a single flea can cause serious, long-term itching and skin irritation. A bad case of FAD can cause your cat to lick and scratch so aggressively – most often at the base of the tail or hind quarters – that he loses a significant amount of hair on that part of his body.

Sometimes dry, itchy skin can induce or aggravate a hyperesthesia condition. This is more common in cats fed a dry food diet.

Another cause of the condition might be seizures. Or more precisely, feline hyperesthesia may be a type of  seizure disorder. Some kitties experience grand mal seizures during an episode of hyperesthesia or right afterwards. Experts theorize the syndrome might be caused by a problem with electrical activity in areas of the brain that control grooming, emotions and predatory behavior.

It may also be a form of obsessive compulsive disorder, with the obsession being fearfulness and/or grooming and/or aggression. Also, seizure activity is known to lead to obsessive compulsive behavior.

Another theory is that certain breeds are predisposed to develop mania as a result of stress. Oriental breeds seem to have more hyperesthesia than the general population of felines, and stress often seems to be the trigger for these kitties.

Also, cats with the condition have been found to have lesions in the muscles of their spine. It’s possible the lesions cause or contribute to the sensations and symptoms that are a feature of hyperesthesia.


A diagnosis of feline hyperesthesia is arrived at through eliminating other conditions and diseases that cause similar symptoms and behavior, including:

  • skin conditions (allergies, parasites, infections
  • hyperthyroidism
  • poisoning
  • underlyking painful conditions of the back, spine, joints or muscles; also, pain associated with bite injuries, abscesses, anal sac disease, organ damage or cancer
  • a problem in the brain (trauma, tumors, infection)

It could be beneficial for you to video your kitty during an episode of what you suspect is hyperesthesia, and take the video with you to your vet appointment.

The vet should perform a physical exam on your kitty, take a behavioral history, and order a complete blood count, chemistry profile and thyroid hormone level test. Other diagnostic tests might also be required, for example, skin tests and x-rays. It’s possible your vet will make a referral to another DVM who specializes in dermatology or neurology.

When all other potential causes for your pet’s symptoms have been ruled out or treated, feline hyperesthesia can be confidently diagnosed.

Treatment of True Feline Hyperesthesia

The treatment for feline hyperesthesia syndrome involves reducing stress on the cat. However, I recommend looking at what you’re feeding your cat first. She should be eating a balanced, species-appropriate diet that contains no carbs, moderate amounts of animal fat, and high levels of animal protein. This will help eliminate any food allergies she may be dealing with, and will improve the condition of her skin and coat. You can also consider supplementing with a rich source of omega-3 fatty acids like krill oil.

To address stress-related triggers, you’ll need to take steps to make your cat as comfortable as possible with his living arrangements. This means building a great deal of consistency in your cat’s daily routine, while at the same time enriching the five key areas of his environment, including:

  • Safe, secure food, water and litter box locations.
  • His own place to climb, scratch, rest and hide.
  • Consistency in all your interactions with him.
  • Appropriate sensory stimulation.
  • The company of another or other non-adversarial cats.

Set aside time each day to play with your cat. This helps him get aerobic exercise and gives him the chance to flex his hunter muscles. Use interactive toys like a feather wand or a toy at the end of a string. Many cats also love chasing laser toys, ping pong balls and even rolled up bits of paper. Since cats have very short attention spans, try to break up playtime into three or four short sessions a day.

Drug Therapy

Giving your cat anti-depressants, anti-convulsants or drugs to curb obsessive behavior should be considered only as a last resort.

A species-appropriate diet, environmental enrichment, and natural remedies like Spirit Essences or OptiBalance pet formulas should go a long way toward alleviating the stressors in your cat’s life that may trigger episodes of hyperesthesia.

I have had good success in reducing symptoms using adjunctive therapies. Acupuncture can commonly reduce the “nerve wind up” many of these cats experience. Chiropractic care can also reduce the dermatome neuritis hyperesthetic cats are plagued with. Tellington Touch, a special form of massage, can also help reduce skin sensitivity in some cats. I’ve also had good success with kitties using homeopathic Aconitum and Hypericum orally to help dampen emotional and neurologic reactivity that can lead to physiologic symptoms.

This post was republished with permission. Dr. Becker is the resident proactive and integrative  wellness veterinarian of HealthyPets.Mercola.com. You can learn holistic ways  of preventing illness in your pets by subscribing to Mercola Pet’s free newsletter. 

Photo by Luke Hayfield Photography, Flickr Creative Commons

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165 Comments on Feline Hyperesthesia Syndrome

  1. Hi Ingrid,
    So, we also got Amber’s blood work done. And it shows a slightly high creatinine level (within the range). Doc wants to address that first.
    When I told him about her random ‘running scared’ and biting her hind quarters, he said it could be FHS.
    Thank you again for all the awareness you’re spreading.

  2. Hi Ingrid,
    I’m so grateful for this article.
    I’m writing from India.
    My 7 year old, sweet and playful Amber, has been vomiting on and off since 4 days.
    Our vet, who is India’s first cat specialist, is trying to find out the cause.
    Meanwhile, I’ve earlier noticed her running scared and licking her lower torso, a few times, and didn’t pay much attention to it.
    Today, she jumped up from her nap and dashed off. That seemed strange!
    And when I googled a bit, I came across this page.
    We’re taking her back to the vet tomorrow. And will update what he says.

  3. We found our kitty outside in the snow when we moved into our house almost 2 years ago. We noticed that she has not grown much (she’s about 1-2 pounds bigger than when we found her, almost like she’s a dwarf kitty). After about a month, she started sticking her tongue out at random. About two months ago she started dropping onto her back, biting and clawing at her backend and tail (she has lost hair, has lesions) and twitching. She does this a few times a day. We have treated for fleas and given baths, but not sure what is going on with her.

  4. 10/2018 About 2/3 weeks ago my cat started this really awful meowing and chasing her tail. I took her to the vet and she had fleas. 3 weeks later she is doing the same exact thing. This almost always only occur in the evening 6/7 she really scaring me. She won’t let the vet touch her so it’s next to impossible to get examined. She had general anesthesia the day I took her and stayed the night. Diagnosis FLEAS, really. I’m terrified that she has an illness and I don’t know what to do. Her name is Kai and she’s 3yrs old. Please respond!!

  5. My beloved cat Mickey Mouse aka Bubbee died from this & he wasnt quite a yr old. 1 day he was fine doibg fun cat things exploring climbing he is a very curious guy hes always showing off for me showing me all the cool things he can do like climb trees run fast in front of me if im doing any project Bubbee is right there assuming i need him to be a pary of the project. i was outside in back yard when he just started running in big circles & kept looking at tge tree then th fence like he was being chasec by something i brought him inside to calm him down when i went to sleep he was just staring at the floor in a trance i put him on a blanket and had cool washcloth and cooled him off he became paralyzed and slowly shut down til he died. it was the hardest death ive ever experienced bc i didnt know how to help him. i thought the whole time he must have gotten bit by rattle snake or got poisoned somehow. I wish i could have saved him he was a great lil buddy that died way too young 🙁

  6. My 13 yeaar olfd cathas been acting like this. I can’t touch her past the head anymore as she hollers and I feel the coat shimmy! She has not been to the vet since spayed at 6 months of age. Indoor cat completely. Never goes outside. I know this is what she has, tries to clean her tail at the crook of it, can’t, then hisses at me because her nail gets stuck then. When she’s through trying, she purrs for me as long as I don’t touch her back. She doesn’t like anyone or will see anyone else. My husband thinks asking her to the vet will stress her out and kill her.. plus I can’t afford a large vet bill. I don’t know what to do@?

  7. My young tabby cat is showing the symptoms described above since two days ago, but her skin and coat are perfect, I do not see anything missing, ripped or red. Vet did not find anything wrong, but gave her steroids (not sure why). I have video of this aggressive and scary behavior. This is very strange, she is usually very calm, curious and playful. Should I keep giving her steroids that vet has prescribed? I feel that without diagnosis she should not be taking any meds. Please help 🙁 I feel awful and my kids are afraid of her now. I want to help.

      • It stopped yesterday. She is up to date on her tick-n-flea meds, but i did remove a tiny dead tick from her eyelid. I know ticks can cause very sharp lower back spasm pains in humans (happened to my husband). If my cat starts acting up again, I will take her for 2nd opinion to search for a reason.

  8. Hi my cat is two years old and just resently he mouth started twitching and then an excessive amount of saliva would come out but she would be fine within minutes, this happened around three times a day but stoped after two days. But today she was in the living room and then ran into my room and acted like (I’m not sure how to describe this) she lost her legs and was flopping all over the place. Once she was done she was breathing really heavily she’s fine now but I’m not sure if it’ll happen again. I’m really worried please help me.

  9. I have a 13 year old Pixie Bob that I love dearly. She has always had allergy issues since a baby. I did try and treat her once with what the vet recommended a few years back not good she stopped eating lost two lbs ect. Now my husband passed away almost 2 years ago and she loved him as well as myself. Sometimes she starts running from room to room but then makes a bowel movement. A vet told me about 5 years ago she has ocd with her grooming on her lower belly area but that its okay. They wanted to express her bowels many years ago but I didnt let the vet then do that I thought honestly it was unnecessary. Sorry trying to give you all a full background here. So about a year ago and I did bring her to the vet she got a clean bill of health and of course she did not do the twitching, licking at the vets when you touched her spine area close to her nub (pixie bobs dont have tails). She is so lovable and I try and give her a good amount of attention. She rencently stopped jumping on the higher shelf of her cat scratcher. I thought maybe shes just getting older but she is able to jump on the bed which is high enough up so maybe not. I recently put her on cosequin which was recommended by the vet a year ago. I honestly do not notice any difference she still licks me and starts to nibble at me a bit when you touch this area of her spine and closer to her nub. They did want me to do xrays, bloodwork ect but honestly I just could not afford it. I want to help her I love her to pieces but I am not sure if this is really her hurting or whats going on. I have been feeding her the same premium senior food with chicken and no fillers for a few years now. I really dont know what to do. I really want to help her though. Thanks Jackie

    • Based on your description, I would guess what you’re seeing is a pain reaction. I do think bloodwork and/or x-rays would probably give you some answers.

    • I just wonder if it is actually hyperesthesia. Again, I would love to do blood work X-rays etc, however $ is an issue.

  10. my purcy started biting his tale 5 days ago. he is 2 and the sweetest thing. does not have a mean bone in his body. but when he looks at his tale he growls and hisses and bites it. he actually bit the tip off. his back will twitch the whole time. he looks terrified of the tale and acts as though he sees other scarey things. the vet gave anxiety medication and that’s it. she really didn’t know. I wrapped the tale with black bandage and that helps if it stays on. plus the pills make him sleep. my heart is breaking. he needs help

    • Cindy, I’ve been told to get my cat who is suspected of suffering from hyperesthesia in for acupuncture asap. I’m going to make an appointment first thing tomorrow. Maybe you’d want to try the same. There shouldn’t be any harm in it anyway. I want to try this before resorting to drugs.

  11. Hello,

    I very concerned about my cat Riley. Riley found me about 3 years ago as a stray. I am guessing he’s around 4 years old now. Four hours ago Riley began with intensive reactions as though he was being bit by something like a spider or a flea, but quickly ruled it out (I have 3 other cats who are fine). Riley then began dashing from one room to another, climbing the ladder to the loft then jumping the ceiling beams in my cabin. It was like mentioned above as though he was being chased by something/hallucinating. His eyes were dilated maybe due to fear. He was also panting/breathing hard. I continued to watched him as I sat next to him on my bed, watching his back twitch uncontrollably. I also noticed a “ridge line’ on the right side of his spine. When I tried to feel the ridge, he immediately let me know that it hurt him as he hissed and growled at me. Riley’s whole body is ultra sensitive to touch except his head. He would also turn aggressively to bite his front leg or tail followed by licking. I immediately called my vet only to find she is on vacation for a week. I then went to the internet and typed ” nerve spasms in cats. I then found this website. I believe Riley is a “classic” case of hyperesthesia syndrome. After reading the complete website I tried to comfort Riley, trying to calm him down, keep him quiet and assure him that he was O.K. It has help a little, but the spasms still continue (not as intense). How long do the spasms last? It’s now going on four hours. How often does this happen? I read that symptoms worsen over the years. How do they worsen? If these symptoms continue to happen to Riley over the years and getting worse, it sounds like I would be allowing Riley to suffer. Am I right to think this?

    I also want to give a little more background information on Riley. First, right from the beginning, when I adopted Riley, there were three noticeable observations. One – Riley has a left eye that is not normal almost like a retardation trait. I always felt there was something not right about Riley but still a good lovable cat. Two – Riley’s bowel movements are the worst!! Very soft and smelly. Once in a great while he will surprise me with a normal bowel movement. Three – Never liked being touched on his back end.

    The vet has seen him a few times and has always given him a clean bill of Health.

    Second, Riley does have some obsessive traits. One – He will sit for an hour or two by the back door, he smells or hears stray cats that I free feed outside on my deck. Two – In the morning he waits for my husband to leave by the front door. When the sun is out and hits the glass on the door it shines a light when the door opens and Riley loves to chase the light. Once my husband has opened and closed the door and left for work, Riley will continue to wait for the light to appear again. Third – At feeding time Riley has a boxing ritual that he shares with my other cat Rowen, twice a day as they both wait for the food to be prepared. Forth – Riley loves watching the birds and squirrels for hours. Are these obsession enough to trigger an episode?

    As far as the diet goes I only purchase premium cat food for my cats. They all receive dry and wet food twice a day. The wet is Salmon and white fish with vegetables and gravy blend and the dry is a Salmon and Venison with vegetables and fruit. It is also grain free.

    My husband and I are going through financial hardships right now. I am just about 90% positive that Riley has hyperesthesia syndrome. I don’t want to spend a fortune for my vet to run all the test that will probably come out negative just to try to rule out the possible prognosis, especially when I am feeling pretty positive that Riley does have this syndrome.

    I like the sound of the homeopathic advice given above (Aconitum or Hypericum) does anyone have personal experience using on either one on cats?
    Also is fish oil the same as Omega -3?

    Any other advice would be welcoming!!

    • Re: bad stools, sounds like he has food sensitivities. Our local holistic vet says avoid all types of fish. I tested my cat w/Hemopet (expensive but worth it) and found she’s allergic to salmon and duck. I got her on limited ingredient diets based on chicken or turkey and no soft BMs since.
      Re: hyperesthesia, I’ve been told to get my cat in for acupuncture asap. I’m hoping to get her in tomorrow; can’t stand to see her suffer much longer. I’ll try to find my way back here to comment on whether it works.

        • Vet says my cat does not have hyperesthesia cuz she appears to be itchy not painful. Regardless i got her “acquapuncture” per vet’s recommendation, 3 punctures around head & neck area with vitamin B12 and approx 5 along her back with diluted … I can’t rem what the injectable form of pred is… Diluted to only 4 mg. Cat relaxed somewhat almost immed and within hours she was calm, no longer licking scratching chewing herself raw. Unknown whether it’s the acupuncture or pred or both. Vet says only need 1 appt a week. I’m just so relieved that my poor girl is comfortable now & wish someone had suggested acupunture years ago! (What would it have hurt to TRY???)

          • Keep us posted on how she’s doing, Alana. Since you did both the pred and the acupuncture at the same time, it’s impossible to tell which worked so quickly, but all that matters is that she’s doing better!

  12. Two weeks ago I adopted a 3-legged cat, he was feral and got right front leg caught in a trap. Sadly he was injured and outdoors for a while before my petsitter friend trapped him and got him to a clinic. They amputated the leg in two separate surgeries (first to elbow then to shoulder) and he also had surgery on some of the arteries under the arm. First few days here were ok. Then on day 5 he suddenly started cry/hiss behavior as described in this feline hyperesthesia article. He will cry and turn to bite at his butt and hop away as fast as he can and will hiss at me if I am anywhere near him. I thought he was having phantom pain and so took him to the vet. They found no one point of pain but gave him a pain shot and 2 weeks of gabapentin. So far he is still having some of these cry/hiss episodes. Thinking he was doing too many stairs here so close to surgery dates (first week of March) I now confine him to one floor and try to limit jumping. Twice he has entered the bathroom and spun crazy circles almost like a dog chasing his tail. First one freaked me out, second one was not as scary. I just turned off the light and left the room and he stopped spinning. Being as he has only 3 legs he spins til his back legs go out from under him then gets back up and spins more, alternating directions. I was sure he was hallucinating. My guy has almost all of the “symptoms” described in the article above, I have not witnessed hair pulling although he still is growing hair back from the surgeries. I am going to mention this to my vet at follow-up and see what they think.

    • I’ll be interested to hear what your vet thinks, Melinda. It sounds like hyperesthesia symptoms, but I also wonder whether this may be a reaction to adjusting to being without the leg, and/or possible nerve damage during the surgery? And bless you for taking this guy in and giving him a chance at a happy life!

    • I found a stray cat with broken front leg too; suspect he was caught in a trap. But he adjusted to amputation perfectly fine; no issues. Have you tried limited ingredient high quality diet? Acupuncture? I’m working on these w/my cat who’s been ruled out for allergies, organ problems, etc. I’ll try to get back here & let you know if the acupuncture works for my cat; maybe it’d work for yours, & little risk / harm if it doesn’t…

  13. My 8 year old cat began twitching, biting and pulling the hair out on her back when she was 6. She also began frequent vomiting her food with an occasional hair ball. It was painful to watch her back twitching as if she was being bitten by something. We had moved 6 months prior to the onset of this behavior during which time she was fine. When I had her vetted, they ran several tests, including a thyroid test and a skin scraping looking for possible mites. Though she had been flea treated, they spent a lot of time going over every inch of her body looking for possible fleas and evidence of their development stages. All tests were negative for irritants. Her skin appeared to be healthy, not dry and scaly. Finally, she was diagnosed with Inflammatory Bowel Disease (IBD) and prescribed an Rx for Z/D, a low allergen food. She was also given a solution to help with dehydration. After 4 days of weaning her completely off of her old food and feeding her only the prescribed wet and dry food, supplemented with an additional dose of Omega-3 oil, the vomiting stopped. Fortunately, her vomiting was not combined with diarrhea, which is common with this diagnosis. The twitching on her back also stopped and the vomiting changed from daily to several weeks in-between. Recently, I attempted to mix her Rx food with a natural skin and sensitive stomach blend (for economical reasons) but the frequent vomiting returned so the change was not successful. I would be interested to hear what other cat parents have to share re: this issue. Thank you for this opportunity to share my Bella’s story.

      • My soon to be three year old Sonny has just started showing symptoms. I’m ruling out fleas or mites, as I have three other cats and no one else, except my 6 yr. old Tifa has exhibited signs of this. Sonny’s seem to happen more often, a couple times a day. I’m going to administer omega-3 more often and see what happens, also gonna try plugging in a fresh Feliway. Katherine, I also have an 18 yr. old, Wicket, that has battled IBD and more recent, colitis. He’s gone to an all ‘wet food’ diet for some time now, but a grain free and limited ingredient diet. There are some good ones that he’s done well on at the pet stores. I stay away from chicken and turkey. He gets mostly venison, some duck and lamb. He does take an anti-inflammatory every day but I’ve worked in some other ‘additives’ into his food that I happened across from Vitality Science. They have a protocol for resistant diarrhea and vomiting cats. He’s been using the products for over four years, while battling this since he was 4 – 6 yrs old. It progressively got worse. I can’t believe how well he’s doing, regardless, with the muscle wasting he had. I wish I would have discovered treatment sooner. Good luck! Kitty prayers!

    • Our kitty developed this out of the blue ~ 5 yrs ago. We did all the traditional vetting. No issues found, no treatments successful. Then we Treated w a fab vet acupuncturist for only 3 sessions, changed to grain free food, occasional omega oil on food has been successful. We occasionall have a flare when we have a household change in routine. Will have a re-tweet w acupuncture for flares.

  14. Hello everyone,

    I’ve been reading a lot of your comments, I see a lot of helpful stuff in here and I’m hoping you could direct me in the right path.
    My little 3 year old fur baby has FHS and I’m going to be adopting a foster kitty. I decided my little girl could use the company, since I’m often not at home, due to work and school.

    I’m looking for any articles that would help instruct me for proper introductions for FHS kitty to a newcomer.

    Thanks in advance! 🙂

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